SCHEMBL17072133

SCHEMBL17072133

CCc1cc(C(C)(C)I)cc(C(C)(C)C(C)(C)C)c1OC

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17072151 0.89 ALDH1A1 (0.36) PTGS2
SCHEMBL14999403 0.87 RARG (0.33) PTGS2
SCHEMBL17072152 0.81 DHFR (0.40) PTGS2
SCHEMBL17072137 0.81 NR3C2 (0.33)
SCHEMBL21547601 0.79 PTGS2 (0.36) PTGS2
SCHEMBL17072135 0.79 PTGS2 (0.32) PTGS2
SCHEMBL13368066 0.76 RXRA (0.40) PTGS2
SCHEMBL15002985 0.72 RARG (0.33) PTGS2
SCHEMBL17072231 0.72 PTGS2 (0.32) PTGS2
SCHEMBL18088898 0.72 RARG (0.40) PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9505878-B2 Catalysts and methods for polymer synthesis NOVOMER, INC. (US) 2016-11-29 US disclosed
US-20150252145-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2015-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150252145-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 PTGS2 130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.