Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13452244 | 0.85 | DHFR (0.41) | DHFRALDH1A1LMNASMN1; SMN2PTGS2 | |
| SCHEMBL17072135 | 0.83 | PTGS2 (0.32) | PTGS2 | |
| SCHEMBL17072151 | 0.83 | ALDH1A1 (0.36) | DHFRALDH1A1PTGS2 | |
| SCHEMBL17072133 | 0.81 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL17286706 | 0.77 | HSD11B1 (0.40) | DHFRALDH1A1LMNASMN1; SMN2CYP2C19 | |
| SCHEMBL17072149 | 0.76 | — | — | |
| SCHEMBL17072137 | 0.76 | NR3C2 (0.33) | ALDH1A1SMN1; SMN2ESR1ESR2 | |
| SCHEMBL13310100 | 0.75 | DHFR (0.44) | DHFRALDH1A1LMNASMN1; SMN2PTGS2 | |
| SCHEMBL14999487 | 0.75 | PTGS2 (0.39) | DHFRALDH1A1LMNASMN1; SMN2PTGS2 | |
| SCHEMBL10044449 | 0.73 | DHFR (0.43) | DHFRALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9505878-B2 | Catalysts and methods for polymer synthesis | NOVOMER, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-20150252145-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150252145-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | PPOX, COASY, SOD1 | DHFR 941/4885ALDH1A1 2255/4885LMNA 3764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.