SCHEMBL23212916

SCHEMBL23212916

CCCCC(CC)CSc1ccc(C=O)c(O)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.39
LMNA P02545 2/20 0.36
TRIM24 O15164 1/20 0.36
TRIM33 Q9UPN9 1/20 0.36
ALDH1A1 P00352 6/20 0.34
CYP3A4 P08684 3/20 0.34
CA2 P00918 3/20 0.34
MAPK1 P28482 2/20 0.33
TSHR P16473 2/20 0.33
KDM4E B2RXH2 1/20 0.33
BCL2L1 Q07817 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
PIK3CD O00329 1/20 0.32
PIK3CA P42336 1/20 0.32
PIK3CB P42338 1/20 0.32
PIK3CG P48736 1/20 0.32
PRKDC P78527 1/20 0.32
CA1 P00915 1/20 0.32
CA4 P22748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21575606 0.77 ALDH1A1 (0.43) LMNAALDH1A1CYP3A4CA2MAPK1
SCHEMBL17075433 0.76 TYR (0.47) TYRTRIM24TRIM33ALDH1A1PIK3CD
SCHEMBL11225290 0.74 TYR (0.49) TYRLMNATRIM24TRIM33ALDH1A1
SCHEMBL31012110 0.72 BDKRB2 (0.43) LMNAALDH1A1CYP3A4CA2MAPK1
SCHEMBL21575602 0.71 SLC6A4 (0.41) ALDH1A1CYP3A4CA2TSHRKDM4E
SCHEMBL30570811 0.71 ALDH1A1 (0.51) LMNAALDH1A1CYP3A4CA2MAPK1
SCHEMBL28985736 0.71 ALDH1A1 (0.51) LMNAALDH1A1CYP3A4CA2MAPK1
SCHEMBL18435314 0.71 SLC16A3 (0.39) TYRLMNAALDH1A1CYP3A4KDM4E
SCHEMBL17075432 0.71 TYR (0.50) TYRTRIM24TRIM33ALDH1A1TSHR
SCHEMBL31012109 0.70 CA2 (0.43) LMNAALDH1A1CYP3A4CA2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114829348-B Coumarin glyoxylates for LED photocuring 意大利艾坚蒙树脂有限公司 2024-08-23 CN disclosed
US-11981650-B2 Coumarin glyoxylates for LED photocuring IGM RESINS ITALIA S.R.L. (IT) 2024-05-14 US disclosed
US-20240067620-A1 COUMARIN GLYOXYLATES FOR LED PHOTOCURING IGM RESINS ITALIA S.R.L. (IT) 2024-02-29 US disclosed
EP-4041719-A1 COUMARIN GLYOXYLATES FOR LED PHOTOCURING IGM Resins Italia S.r.l. (IT) 2022-08-17 EP disclosed
CN-114829348-A Coumarin glyoxylate for LED photocuring 意大利艾坚蒙树脂有限公司 2022-07-29 CN disclosed
WO-2021070152-A1 COUMARIN GLYOXYLATES FOR LED PHOTOCURING IGM RESINS ITALIA S.R.L. (IT) 2021-04-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067620-A1 COUMARIN GLYOXYLATES FOR LED PHOTOCURING AGXT, GRHPR, GLO1 TYR 57/4885LMNA 625/4885TRIM24 3725/4885
US-11981650-B2 Coumarin glyoxylates for LED photocuring AGXT, GRHPR, GLO1 TYR 57/4885LMNA 625/4885TRIM24 3725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.