Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 9/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14979618 | 0.86 | CYP1A2 (0.43) | DGAT1MCHR1LIPECHRNA7GPR119 | |
| SCHEMBL17082348 | 0.84 | CHRNA7 (0.41) | DGAT1MCHR1LIPECHRNA7GPR119 | |
| SCHEMBL518294 | 0.83 | FAAH (0.46) | FAAH | |
| SCHEMBL13691949 | 0.83 | LIPE (0.38) | DGAT1MCHR1LIPECHRNA7GPR119 | |
| SCHEMBL15525341 | 0.75 | DGAT1 (0.57) | DGAT1GPR119 | |
| SCHEMBL31401120 | 0.75 | DGAT1 (0.57) | DGAT1GPR119 | |
| SCHEMBL14979619 | 0.73 | FAAH (0.51) | MCHR1LIPECHRNA7GPR119BCHE | |
| SCHEMBL17082354 | 0.71 | FAAH (0.49) | MCHR1LIPEGPR119BCHEFAAH | |
| SCHEMBL25354847 | 0.71 | LTA4H (0.46) | LIPEACACBKDM4ETSHR | |
| SCHEMBL16866583 | 0.70 | FAAH (0.48) | MCHR1LIPEGPR119BCHEFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265578-B1 | AZETIDINE DERIVATIVES | VERNALIS R&D LTD (GB) | 2015-09-16 | — | — | EP | disclosed |