Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SELP | P16109 | 2/20 | 0.40 |
| ▸ | SELE | P16581 | 2/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | SELL | P14151 | 1/20 | 0.38 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090493 | 0.88 | TLR7 (0.40) | NR1H4FABP4CA12CA9 | |
| SCHEMBL10113577 | 0.85 | HDAC6 (0.51) | NR1H4SELPSELEHPSEPPARG | |
| SCHEMBL13564900 | 0.85 | PTGS1 (0.41) | HDAC11HDAC8HDAC6 | |
| SCHEMBL17090501 | 0.83 | ADRB2 (0.46) | NR1H4FABP4ADRB2ADRB3SELP | |
| SCHEMBL13564903 | 0.83 | L3MBTL1 (0.34) | CYP1A2CYP2C19HDAC11HDAC8CA12 | |
| SCHEMBL13565777 | 0.81 | UQCRB (0.42) | CYP1A2CA12CA1CA2CA9 | |
| SCHEMBL13565413 | 0.81 | ALDH1A1 (0.48) | CYP1A2CYP2C19 | |
| SCHEMBL13564773 | 0.81 | L3MBTL1 (0.48) | CYP1A2 | |
| SCHEMBL17089972 | 0.81 | PKM (0.47) | PPARGPPARA | |
| SCHEMBL13565885 | 0.80 | ALDH1A1 (0.50) | CA12CA2CA9HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |