Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | LOX | P28300 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17091853 | 0.88 | LOXL2 (0.43) | VNN1LOXL2LOXTYMSHDAC3 | |
| SCHEMBL17092298 | 0.82 | KCNH2 (0.45) | VNN1HDAC3HDAC4HDAC6HDAC1 | |
| SCHEMBL17092327 | 0.78 | TACR1 (0.40) | VNN1HDAC6HDAC1HDAC8TACR1 | |
| SCHEMBL17092406 | 0.76 | TACR1 (0.38) | HDAC3HDAC4HDAC6HDAC1HDAC7 | |
| SCHEMBL17092309 | 0.74 | P2RX7 (0.38) | HDAC3HDAC4HDAC6HDAC1HDAC7 | |
| SCHEMBL15645684 | 0.74 | HSD17B2 (0.56) | MMP13MEN1KMT2APOLBHPGD | |
| SCHEMBL30016477 | 0.67 | MLYCD (0.48) | VNN1LOXL2HDAC4MLYCD | |
| SCHEMBL15648032 | 0.67 | MLYCD (0.48) | VNN1LOXL2HDAC4MLYCD | |
| SCHEMBL29593796 | 0.67 | LOXL2 (0.59) | VNN1LOXL2LOXHDAC4MMP13 | |
| SCHEMBL14284330 | 0.67 | LOXL2 (0.59) | VNN1LOXL2LOXHDAC4MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10035790-B2 | RORγ modulators | EXELIXIS, INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-20150266856-A1 | RORGamma Modulators | EXELIXIS, INC. | 2015-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266856-A1 | RORGamma Modulators | RORB, RORA, RORC | VNN1 4754/4885LOXL2 3109/4885LOX 3285/4885 |
| US-10035790-B2 | RORγ modulators | RORB, RORA, RORC | VNN1 4804/4885LOXL2 2643/4885LOX 2925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.