SCHEMBL1709332

SCHEMBL1709332

CCC(=O)NCCC(=O)O

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
ECE1 P42892 4/20 0.58
FAAH O00519 2/20 0.47
CNR1 P21554 2/20 0.47
CNR2 P34972 2/20 0.47
PLA2G2A P14555 1/20 0.47
FFAR3 O14843 2/20 0.43
HDAC3 O15379 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
RECQL P46063 1/20 0.43
TSHR P16473 1/20 0.42
EPHX2 P34913 2/20 0.41
CASP2 P42575 1/20 0.40
ADRA1A P35348 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30744271 0.91 MEN1 (0.52) MEN1KMT2AECE1FAAHCNR1
SCHEMBL1912627 0.86 MEN1 (0.70) MEN1KMT2APLA2G2ARECQLEPHX2
SCHEMBL45902 0.84 MEN1 (0.74) MEN1KMT2APLA2G2AEPHX2CASP2
SCHEMBL4635358 0.83 CASP2 (0.59) MEN1KMT2AECE1FAAHCNR1
SCHEMBL20009655 0.82 MEN1 (0.71) MEN1KMT2APLA2G2ATSHREPHX2
SCHEMBL21424846 0.82 ECE1 (0.45) MEN1KMT2AECE1FAAHCNR1
SCHEMBL19400283 0.82 MEN1 (0.71) MEN1KMT2APLA2G2ATSHREPHX2
SCHEMBL19400289 0.82 MEN1 (0.71) MEN1KMT2APLA2G2ATSHREPHX2
SCHEMBL5522638 0.82 MEN1 (0.71) MEN1KMT2APLA2G2ATSHREPHX2
SCHEMBL9265462 0.82 MEN1 (0.71) MEN1KMT2APLA2G2ATSHREPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090186853-A1 COMPOSITIONS COMPRISING N-PROPANOYL DERIVATIVES OF AMINO ACIDS, AMINOCARBOHYDRATES AND DERIVATIVES THEREOF YU RUEY J 2009-07-23 US claimed
EP-1865953-A4 COMPOSITION COMPRISING N-PROPANOYL DERIVATIVES OF AMINO ACIDS, AMINOCARBOHYDRATES AND DERIVATIVES THEREOF YU RUEY J (US) 2008-04-30 EP claimed
EP-1865953-A2 COMPOSITION COMPRISING N-PROPANOYL DERIVATIVES OF AMINO ACIDS, AMINOCARBOHYDRATES AND DERIVATIVES THEREOF Yu, Ruey J., Dr. (US) 2007-12-19 EP claimed
WO-2006101940-A2 COMPOSITION COMPRISING N-PROPANOYL DERIVATIVES OF AMINO ACIDS, AMINOCARBOHYDRATES AND DERIVATIVES THEREOF YU, RUEY, J. (US) 2006-09-28 WO claimed
US-20060211754-A1 Compositions comprising N-propanoyl derivatives of amino acids, aminocarbohydrates and derivatives thereof YU RUEY J 2006-09-21 US claimed
US-20050171194-A1 Enlargement of mucocutaneous or cutaneous organs and sites with topical compositions YU RUEY J (US) 2005-08-04 US claimed
US-11873291-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-01-16 US disclosed
WO-2023168367-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS IMMUNESENSOR THERAPEUTICS, INC. (US) 2023-09-07 WO disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
CN-110832042-B Method for producing aqueous pigment dispersion 花王株式会社 2022-10-14 CN disclosed
WO-2021081495-A1 POLYMERIC NANOPARTICLES FOR INTRACELLULAR PROTEIN DELIVERY THE JOHNS HOPKINS UNIVERSITY (US) 2021-04-29 WO disclosed
EP-2880033-B1 CYCLIC UREA- OR LACTAM-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND THE USES THEREOF PURDUE PHARMA LP (US) 2020-06-17 EP disclosed
EP-3103797-B1 2,5-DIOXOIMIDAZOLIDIN-1-YL-3-PHENYLUREA DERIVATIVES AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS ALLERGAN INC (US) 2019-04-10 EP disclosed
US-20060116328-A1 Combined use of carnosinase inhibitor with l-carnosines and composition INNOVATIVE VISION PRODUCTS, INC. 2006-06-01 US disclosed
EP-1586332-A1 COMBINED USE OF CARNOSINASE INHIBITOR WITH L-CARNOSINES AND COMPOSITION Innovative Vision Products, Inc. (US) 2005-10-19 EP disclosed
US-20050171194-A1 Enlargement of mucocutaneous or cutaneous organs and sites with topical compositions YU RUEY J (US) 2005-08-04 US disclosed
WO-1997026246-A1 SUBSTITUTED HISTIDINE INHIBITORS OF PROTEIN FARNESYLTRANSFERASE WARNER-LAMBERT COMPANY (US) 1997-07-24 WO disclosed
US-5466858-A Ruthenium catalyst, high selectivity with a carboxylic acid UBE INDUSTRIES, LTD. (JP) 1995-11-14 US disclosed
US-4015008-A N,N-dichloro substituted aminocarboxylic acids as microbiocides NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1977-03-29 US disclosed
US-3950536-A N,N-Dichloro substituted aminocarboxylic acids as bactericides and fungicides BARER SOL JOSEPH 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060116328-A1 Combined use of carnosinase inhibitor with l-carnosines and composition LCT, ADH1C, PON1 MEN1 3044/4885KMT2A 2558/4885ECE1 237/4885
US-11873291-B2 Quinoline cGAS antagonist compounds CGAS, GLS2, GLS MEN1 1514/4885KMT2A 4371/4885ECE1 1039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.