Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.48 |
| ▸ | TACR1 | P25103 | 12/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709392 | 0.95 | MAOA (0.44) | MAOATACR1KDM1AMAOBCCR2 | |
| SCHEMBL1709391 | 0.91 | SSTR3 (0.46) | MAOATACR1KDM1AMAOBCCR2 | |
| SCHEMBL1709387 | 0.89 | SSTR3 (0.44) | MAOAKDM1AMAOB | |
| SCHEMBL1709388 | 0.86 | MAOA (0.45) | MAOATACR1KDM1AMAOB | |
| SCHEMBL1709467 | 0.78 | TACR1 (0.41) | TACR1 | |
| SCHEMBL10033000 | 0.77 | KDM1A (0.44) | MAOATACR1KDM1AMAOB | |
| SCHEMBL1709396 | 0.74 | ALDH1A1 (0.38) | TACR1 | |
| SCHEMBL10033189 | 0.74 | TACR1 (0.39) | TACR1 | |
| SCHEMBL9164285 | 0.73 | TACR1 (0.79) | TACR1 | |
| SCHEMBL4481286 | 0.72 | CCR2 (0.47) | MAOAKDM1AMAOBCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |