Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 6/20 | 0.46 |
| ▸ | TACR1 | P25103 | 7/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | CCR2 | P41597 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.38 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709392 | 0.96 | MAOA (0.44) | SSTR3TACR1MAOACCR2KDM1A | |
| SCHEMBL1709386 | 0.91 | MAOA (0.48) | TACR1MAOACCR2KDM1AMAOB | |
| SCHEMBL1709387 | 0.88 | SSTR3 (0.44) | SSTR3MAOAKDM1AMAOB | |
| SCHEMBL1709467 | 0.79 | TACR1 (0.41) | TACR1 | |
| SCHEMBL1709388 | 0.77 | MAOA (0.45) | TACR1MAOAKDM1AMAOB | |
| SCHEMBL1709396 | 0.74 | ALDH1A1 (0.38) | TACR1 | |
| SCHEMBL4495364 | 0.73 | CCR2 (0.47) | SSTR3MAOACCR2KDM1AMAOB | |
| SCHEMBL4481286 | 0.73 | CCR2 (0.47) | SSTR3MAOACCR2KDM1AMAOB | |
| SCHEMBL10033002 | 0.72 | SLC6A2 (0.37) | TACR1POLB | |
| SCHEMBL1709470 | 0.71 | KDM4E (0.40) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |