Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 6/20 | 0.42 |
| ▸ | TACR1 | P25103 | 4/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709391 | 0.96 | SSTR3 (0.46) | MAOAKDM1AMAOBCCR2TACR1 | |
| SCHEMBL1709386 | 0.95 | MAOA (0.48) | MAOAKDM1AMAOBCCR2TACR1 | |
| SCHEMBL1709387 | 0.83 | SSTR3 (0.44) | MAOAKDM1AMAOBSSTR3KDM4E | |
| SCHEMBL1709388 | 0.81 | MAOA (0.45) | MAOAKDM1AMAOBTACR1KCNH2 | |
| SCHEMBL1709396 | 0.77 | ALDH1A1 (0.38) | TACR1KCNH2KDM4EALDH1A1GAA | |
| SCHEMBL4495364 | 0.76 | CCR2 (0.47) | MAOAKDM1AMAOBCCR2SSTR3 | |
| SCHEMBL4481286 | 0.76 | CCR2 (0.47) | MAOAKDM1AMAOBCCR2SSTR3 | |
| SCHEMBL10033002 | 0.75 | SLC6A2 (0.37) | TACR1KCNH2KDM4EALDH1A1POLB | |
| SCHEMBL1709467 | 0.75 | TACR1 (0.41) | TACR1KCNH2 | |
| SCHEMBL1709470 | 0.74 | KDM4E (0.40) | KDM4EALDH1A1POLBGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |