Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 15/20 | 0.43 |
| ▸ | TP53 | P04637 | 9/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709407 | 0.88 | TP53 (0.39) | TP53EPHX2EPHX1 | |
| SCHEMBL1709489 | 0.87 | OPRM1 (0.37) | SLC6A2SLC6A4 | |
| SCHEMBL1709480 | 0.87 | NPC1 (0.38) | MDM2TP53 | |
| SCHEMBL1709358 | 0.85 | DPEP1 (0.36) | MDM2TP53EPHX2SLC6A2SLC6A4 | |
| SCHEMBL1709359 | 0.84 | USP30 (0.38) | SLC6A2SLC6A4 | |
| SCHEMBL1709459 | 0.83 | CXCR3 (0.34) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10033118 | 0.83 | OPRL1 (0.38) | MDM2TP53EPHX2 | |
| SCHEMBL1709408 | 0.83 | DGAT1 (0.38) | — | |
| SCHEMBL1709409 | 0.80 | POLB (0.38) | SLC6A2SLC6A4 | |
| SCHEMBL1709454 | 0.80 | SLC6A2 (0.40) | EPHX1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |