Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.31 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709358 | 0.82 | DPEP1 (0.36) | SLC6A2MDM2DGAT1SLC6A4TAS1R3 | |
| SCHEMBL1709510 | 0.77 | TACR1 (0.34) | SLC6A4 | |
| SCHEMBL1709459 | 0.74 | CXCR3 (0.34) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1709359 | 0.72 | USP30 (0.38) | SLC6A2DGAT1SLC6A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL1709454 | 0.71 | SLC6A2 (0.40) | SLC6A2CYP2D6SLC6A4SLC6A3TAS1R3 | |
| SCHEMBL1709448 | 0.70 | FFAR4 (0.32) | SLC6A2 | |
| SCHEMBL1709480 | 0.68 | NPC1 (0.38) | MDM2DGAT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1709481 | 0.67 | MDM2 (0.43) | SLC6A2MDM2SLC6A4SLC6A3 | |
| SCHEMBL1709410 | 0.67 | POLB (0.35) | SLC6A2DGAT1SLC6A4SMN1; SMN2 | |
| SCHEMBL1709409 | 0.66 | POLB (0.38) | SLC6A2DGAT1SLC6A4DPEP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |