SCHEMBL1709510

SCHEMBL1709510

Cc1cc(F)ccc1C1C(CC(=O)O)CCCC1N(CCC(C)(C)C)CCC(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 14/20 0.34
CYP3A4 P08684 3/20 0.33
OPRL1 P41146 3/20 0.33
SLC6A4 P31645 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1709513 0.77 SLC6A2 (0.34) SLC6A4
SCHEMBL10033119 0.69 PTGDR2 (0.37) PTGDR2
SCHEMBL1709489 0.66 OPRM1 (0.37) SLC6A4PTGDR2
SCHEMBL1709410 0.65 POLB (0.35) SLC6A4
SCHEMBL1709409 0.65 POLB (0.38) SLC6A4
SCHEMBL10033118 0.65 OPRL1 (0.38) OPRL1PTGDR2
SCHEMBL1709406 0.65 EPHX2 (0.32) SLC6A4PTGDR2
SCHEMBL10032836 0.63 FFAR4 (0.32)
SCHEMBL1709473 0.63 ALDH1A1 (0.38) SLC6A4PTGDR2
SCHEMBL10033069 0.61 MMP3 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012046771-A1 CYCLOALKANE COMPOUND アステラス製薬株式会社 (JP) 2012-04-12 WO disclosed