Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 5/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12421884 | 0.85 | NPC1 (0.49) | HCAR3LMNATSHRNPSR1NPC1 | |
| SCHEMBL6184141 | 0.82 | HCAR3 (0.56) | HCAR3SLC9A1LMNATSHRNPSR1 | |
| SCHEMBL13619476 | 0.81 | LMNA (0.42) | HCAR3LMNATSHRNPSR1NPC1 | |
| SCHEMBL27965846 | 0.80 | HCAR3 (0.40) | HCAR3LMNATSHRNPSR1NPC1 | |
| SCHEMBL17103068 | 0.79 | BRD4 (0.48) | LMNARAB9ASMN1; SMN2HTTMAPT | |
| SCHEMBL15687432 | 0.79 | MAPT (0.53) | HCAR3LMNATSHRNPSR1NPC1 | |
| SCHEMBL17103008 | 0.78 | SLC9A1 (0.52) | SLC9A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2884485 | 0.77 | HCAR3 (0.53) | HCAR3LMNATSHRNPSR1NPC1 | |
| SCHEMBL12380477 | 0.77 | HCAR3 (0.46) | HCAR3LMNATSHRNPSR1NPC1 | |
| SCHEMBL31746474 | 0.76 | KMO (0.46) | LMNARAB9ASMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9415047-B2 | Use of benzo five-membered nitrogen heterocyclic piperazine or piperidine derivatives | Liaoning Emmy Biological Pharmaceutical Co., Ltd. (CN) | 2016-08-16 | — | — | US | disclosed |
| US-20150297586-A1 | USE OF BENZO FIVE-MEMBERED NITROGEN HETEROCYCLIC PIPERAZINE OR PIPERIDINE DERIVATIVES | Liaoning Emmy Biological Pharmaceutical Co., Ltd. (CN) | 2015-10-22 | — | — | US | disclosed |
| EP-2924033-A1 | USE OF BENZO FIVE-MEMBERED NITROGEN HETEROCYCLIC PIPERAZINE OR PIPERIDINE DERIVATIVES | Liaoning Emmy Biological Pharmaceutical Co., Ltd (CN) | 2015-09-30 | — | — | EP | disclosed |
| CN-103833642-A | Use of benzo five-membered azaheterocyclyl piperazine derivatives | LIAONING BEILEI BIOLOG PHARMACEUTICAL CO LTD | 2014-06-04 | — | — | CN | disclosed |
| CN-103833658-A | Benzotriazole-based piperazine compound as well as preparation method and pharmaceutical composition thereof | LIAONING BEILEI BIOLOG PHARMACEUTICAL CO LTD | 2014-06-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150297586-A1 | USE OF BENZO FIVE-MEMBERED NITROGEN HETEROCYCLIC PIPERAZINE OR PIPERIDINE DERIVATIVES | P2RX5, TBXA2R, CYP3A5 | HCAR3 460/4885SLC9A1 837/4885LMNA 1512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.