Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 5/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 8/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29738313 | 0.90 | LPL (0.38) | LPLLIPGPDK2PRMT5WDR77 | |
| SCHEMBL12442308 | 0.90 | LPL (0.38) | LPLLIPGPDK2PRMT5WDR77 | |
| SCHEMBL12781906 | 0.88 | LPL (0.41) | LPLLIPGPDK2 | |
| SCHEMBL17142003 | 0.86 | LPL (0.37) | LPLLIPGPDK2 | |
| SCHEMBL21995601 | 0.86 | LPL (0.37) | LPLLIPGPDK2 | |
| SCHEMBL31050384 | 0.83 | PGR (0.34) | LPLLIPGPDK2 | |
| SCHEMBL26179604 | 0.83 | LPL (0.35) | LPLLIPG | |
| SCHEMBL12781885 | 0.82 | LIPG (0.46) | LPLLIPGPRMT5WDR77 | |
| SCHEMBL12791300 | 0.82 | LIPG (0.42) | LPLLIPGPRMT5WDR77 | |
| SCHEMBL29637486 | 0.82 | LIPG (0.42) | LPLLIPGPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10381572-B2 | Heterocyclic compound and organic light-emitting element comprising same | LG CHEM, LTD. (KR) | 2019-08-13 | — | — | US | disclosed |
| US-20190106391-A1 | COMPOUNDS WITH SPIROBIFLUORENE-STRUCTURES | MERCK PATENT GMBH (DE) | 2019-04-11 | — | — | US | disclosed |
| WO-2017157983-A1 | COMPOUNDS WITH SPIROBIFLUORENE-STRUCTURES | MERCK PATENT GMBH (DE) | 2017-09-21 | — | — | WO | disclosed |
| US-20170018718-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2017-01-19 | — | — | US | disclosed |
| WO-2015152651-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | 주식회사 엘지화학 | 2015-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190106391-A1 | COMPOUNDS WITH SPIROBIFLUORENE-STRUCTURES | TEC, NUDT1, DPYD | LPL 4755/4885LIPG 4611/4885PDK2 157/4885 |
| US-10381572-B2 | Heterocyclic compound and organic light-emitting element comprising same | CRY1, CRY2, PER2 | LPL 2062/4885LIPG 2731/4885PDK2 2847/4885 |
| US-20170018718-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | CRY1, CRY2, PER2 | LPL 2062/4885LIPG 2731/4885PDK2 2847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.