Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.54 |
| ▸ | RXRG | P48443 | 9/20 | 0.54 |
| ▸ | RXRB | P28702 | 8/20 | 0.54 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29927941 | 1.00 | RXRA (0.54) | RXRARXRGRXRBAGBL2PSEN1 | |
| SCHEMBL504122 | 0.87 | RXRA (0.68) | RXRARXRGRXRBAGBL2PSEN1 | |
| SCHEMBL12301741 | 0.86 | TACR1 (0.40) | RXRARXRGRXRBAGBL2PSEN1 | |
| SCHEMBL22774254 | 0.84 | TACR1 (0.40) | RXRARXRGRXRBAGBL2PSEN1 | |
| SCHEMBL30875890 | 0.84 | GRIN2B (0.43) | RXRARXRGRXRBPSEN1PSEN2 | |
| SCHEMBL30151169 | 0.83 | FFAR4 (0.48) | RXRARXRGRXRBTACR1PPARA | |
| SCHEMBL29927377 | 0.83 | PSEN1 (0.40) | RXRARXRGRXRBAGBL2PSEN1 | |
| SCHEMBL22773948 | 0.82 | RXRA (0.54) | RXRARXRGRXRBAGBL2PSEN1 | |
| SCHEMBL29467110 | 0.82 | RXRA (0.54) | RXRARXRGRXRBAGBL2PSEN1 | |
| SCHEMBL10137786 | 0.81 | TACR1 (0.41) | RXRARXRGRXRBAGBL2PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025895-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-01-25 | — | — | US | disclosed |
| US-11787804-B2 | Compositions and methods for modulating hair growth | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-10-17 | — | — | US | disclosed |
| WO-2022212326-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-06 | — | — | WO | disclosed |
| US-20220267300-A1 | SULFONAMIDE DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2022-08-25 | — | — | US | disclosed |
| CN-114761383-A | Sulfonamide derivatives and uses thereof | 诺瑟拉有限公司 | 2022-07-15 | — | — | CN | disclosed |
| WO-2020249669-A1 | SULFONAMIDE DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2020-12-17 | — | — | WO | disclosed |
| US-9334249-B2 | Inhibitors of cytomegalovirus | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-05-10 | — | — | US | disclosed |
| US-20150284348-A1 | INHIBITORS OF CYTOMEGALOVIRUS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284348-A1 | INHIBITORS OF CYTOMEGALOVIRUS | CDKN1A, CCNA1, IFNAR1 | RXRA 1227/4885RXRG 2584/4885RXRB 1758/4885 |
| US-20220267300-A1 | SULFONAMIDE DERIVATIVES AND USES THEREOF | IL1B, IL1A, CASP1 | RXRA 2545/4885RXRG 2943/4885RXRB 2384/4885 |
| US-11787804-B2 | Compositions and methods for modulating hair growth | PC, FH, SLC25A1 | RXRA 2175/4885RXRG 1276/4885RXRB 1673/4885 |
| US-20240025895-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, SLC25A1 | RXRA 2175/4885RXRG 1276/4885RXRB 1673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.