SCHEMBL1716396

SCHEMBL1716396

COc1ccc(CC(C(=O)O)c2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.65
PPARG P37231 1/20 0.59
PPARA Q07869 1/20 0.59
ATM Q13315 1/20 0.53
MMP1 P03956 1/20 0.53
EPHX1 P07099 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
KMT2A Q03164 2/20 0.50
CCKAR P32238 1/20 0.50
CASR P41180 1/20 0.50
MEN1 O00255 1/20 0.50
FPR2 P25090 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6643092 0.94 PPARG (0.63) LDHAPPARGPPARAEPHX1KMT2A
SCHEMBL21959088 0.93 LDHA (0.69) LDHAPPARGPPARACCKAR
SCHEMBL27871541 0.90 LDHA (0.60) LDHAPPARGPPARAATMMMP1
SCHEMBL23494950 0.88 ESR1 (0.63) LDHAPPARGPPARAATMMMP1
SCHEMBL10964998 0.88 ESR1 (0.63) LDHAPPARGPPARA
SCHEMBL4506554 0.88 EPHX1 (0.71) LDHAPPARGPPARAATMMMP1
SCHEMBL6588762 0.88 LDHA (0.57) LDHAPPARGPPARAATMMMP1
SCHEMBL1153337 0.86 LDHA (0.59) LDHAPPARGPPARAKMT2AMEN1
SCHEMBL29174149 0.86 LDHA (0.59) LDHAPPARGPPARAKMT2AMEN1
SCHEMBL2922282 0.86 MITF (0.59) LDHAPPARGPPARAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3689849-B1 PERFUME PRECURSOR TAKASAGO PERFUMERY CO LTD (JP) 2025-01-15 EP claimed
US-20160090556-A1 PRODUCTS COMPRISING MALODOR REDUCTION MATERIALS THE PROCTER & GAMBLE COMPANY 2016-03-31 US claimed
EP-1716159-B1 BICYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS MOMENTIVE PERFORMANCE MAT INC (US) 2011-07-13 EP claimed
EP-1697386-B1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GEN ELECTRIC (US) 2007-10-10 EP claimed
EP-3704117-B1 AZABICYCLO DERIVATIVES FOR TREATING OCULAR DISORDERS ALCON INC (CH) 2026-01-28 EP disclosed
US-12247028-B2 Azabicyclo and diazepine derivatives ALCON INC. (CH) 2025-03-11 US disclosed
EP-4016044-B1 IMPROVED METHOD FOR OPTICALLY CLARIFYING A TISSUE SAMPLE FOR MICROSCOPIC EXAMINATION MobiCron GmbH (DE) 2025-02-05 EP disclosed
US-20240132497-A1 AZABICYCLO AND DIAZEPINE DERIVATIVES ALCON INC. (CH) 2024-04-25 US disclosed
US-11884666-B2 Azabicyclo and diazepine derivatives ALCON INC. (CH) 2024-01-30 US disclosed
CN-107847958-B Switchable digital scent generation and release and vapor and liquid delivery methods and systems 加利福尼亚大学董事会 2024-01-16 CN disclosed
US-20220267328-A1 AZABICYCLO AND DIAZEPINE DERIVATIVES ALCON INC. (CH) 2022-08-25 US disclosed
WO-2022129221-A1 IMPROVED METHOD FOR OPTICALLY CLEARING A TISSUE SAMPLE FOR A LIGHT MICROSCOPY EXAMINATION MobiCron GmbH (DE) 2022-06-23 WO disclosed
EP-1261588-A1 NEW IMIDAZOLE DERIVATIVES ORION CORPORATION (FI) 2002-12-04 EP disclosed
US-20020115621-A1 Macrolide antibiotics PFIZER INC. 2002-08-22 US disclosed
US-6388090-B2 IMIDAZOLE DERIVATIVES CONTAINING BICYCLIC AROMATIC OR AN HETEROCYCLIC RING FUSED WITH BENZENE EXHIBIT AFFINITY FOR ALPHA2 ADRENOCEPTORS SO TREATS THE DISEASE AFFECTED BY ALPHA2 ADRENOCEPTORS, E.G. NUROLOGICAL, PSYCHIATRIC OR COGNITION ORION CORPORATION (FI) 2002-05-14 US disclosed
WO-2002012260-A1 MACROLIDE ANTIBIOTICS PFIZER PRODUCTS INC. (US) 2002-02-14 WO disclosed
US-20010056109-A1 Imidazole derivatives ORION CORPORATION (FI) 2001-12-27 US disclosed
CN-1314906-A Salts of paroxetine SMITHKLINE BEECHAM PLC (GB) 2001-09-26 CN disclosed
WO-2001051472-A1 NEW IMIDAZOLE DERIVATIVES ORION CORPORATION (FI) 2001-07-19 WO disclosed
US-5776983-A ANTIDIABETIC AGENTS, OBESITY, GASTROINTESTINAL DISORDERS BRISTOL-MYERS SQUIBB COMPANY (US) 1998-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11884666-B2 Azabicyclo and diazepine derivatives CHRM3, CHRM5, CHRNA5 LDHA 4752/4885PPARG 410/4885PPARA 633/4885
US-20010056109-A1 Imidazole derivatives ADRB2, ADRB1, ADRA1D LDHA 3424/4885PPARG 1300/4885PPARA 2296/4885
US-20240132497-A1 AZABICYCLO AND DIAZEPINE DERIVATIVES CHRM3, CHRM5, CHRNA5 LDHA 4752/4885PPARG 410/4885PPARA 633/4885
US-20020115621-A1 Macrolide antibiotics MRPL21, NOP2, NPPA LDHA 2182/4885PPARG 2738/4885PPARA 2436/4885
US-20220267328-A1 AZABICYCLO AND DIAZEPINE DERIVATIVES CHRM3, CHRM5, CHRNA5 LDHA 4752/4885PPARG 410/4885PPARA 633/4885
US-12247028-B2 Azabicyclo and diazepine derivatives CHRM3, CHRM5, CHRNA5 LDHA 4752/4885PPARG 410/4885PPARA 633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.