Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.79 |
| ▸ | XDH | P47989 | 2/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 3/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17179811 | 0.89 | ALDH1A1 (1.00) | ALDH1A1XDHABCB1MAPTHPGD | |
| SCHEMBL28024600 | 0.81 | ALDH1A1 (0.78) | ALDH1A1XDHMAPTHPGDKDM4E | |
| SCHEMBL31162964 | 0.80 | ALDH1A1 (0.71) | ALDH1A1XDHMAPTHPGDKDM4E | |
| SCHEMBL19789557 | 0.78 | XDH (0.70) | ALDH1A1XDHMAPTHPGDKDM4E | |
| SCHEMBL16942322 | 0.78 | ALDH1A1 (0.76) | ALDH1A1XDHABCB1 | |
| SCHEMBL10608985 | 0.77 | ALDH1A1 (0.67) | ALDH1A1XDHMAPTHPGDKDM4E | |
| SCHEMBL28545861 | 0.76 | ALDH1A1 (0.78) | ALDH1A1XDHABCB1HPGDKDM4E | |
| SCHEMBL28213500 | 0.75 | ALDH1A1 (0.71) | ALDH1A1XDHMAPTHPGDKDM4E | |
| SCHEMBL28302550 | 0.75 | ALDH1A1 (0.71) | ALDH1A1XDHMAPTHPGDKDM4E | |
| SCHEMBL23202794 | 0.74 | ALDH1A1 (0.62) | ALDH1A1XDHMAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150291547-A1 | SMALL MOLECULES FOR EXTENDING THE WELL BEING OF CELLS AND METHODS OF USE THEREOF | NANYANG POLYTECHNIC (SG) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291547-A1 | SMALL MOLECULES FOR EXTENDING THE WELL BEING OF CELLS AND METHODS OF USE THEREOF | TERT, POT1, TERF2 | ALDH1A1 2026/4885XDH 2934/4885ABCB1 3994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.