Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oleic Acid SCHEMBL17200214 | 0.75 | L3MBTL1 (0.60) | HTR1AHTR7HTR2A | |
| Oleic Acid SCHEMBL17200212 | 0.75 | L3MBTL1 (0.60) | HTR1AHTR7HTR2A | |
| SCHEMBL12803738 | 0.75 | ADRA2A (0.53) | HTR1ADRD2DRD3CYP3A4ADRA2A | |
| SCHEMBL28527312 | 0.71 | HTR1A (0.60) | HTR1ADRD2HTR7HTR2AHTR1D | |
| SCHEMBL28519578 | 0.71 | HTR1A (0.60) | HTR1ADRD2HTR7HTR2AHTR1D | |
| SCHEMBL11081886 | 0.71 | HTR1A (0.58) | HTR1ADRD2DRD3HTR7HTR2A | |
| SCHEMBL2773513 | 0.70 | ADRA1B (0.39) | HTR1ADRD2DRD3ADRA1DADRA1A | |
| SCHEMBL28520172 | 0.69 | CNR1 (0.61) | HTR1ADRD2HTR7 | |
| SCHEMBL28528626 | 0.69 | CNR1 (0.61) | HTR1ADRD2HTR7 | |
| SCHEMBL28520169 | 0.69 | CNR1 (0.61) | HTR1ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105012306-A | SAA derivative compounds in hypoxic state are capable of reducing eNOS and inhibiting oxidative stress induced diseases | JIANZHI BIOLOG TECHNOLOGY CO LTD | 2015-11-04 | — | — | CN | disclosed |
| WO-2015161510-A1 | SAA DERIVATIVE COMPOUND RESTORES ENOS AND INHIBITS OXIDATIVE STRESS-INDUCED DISEASES IN HYPOXIA | JANSFAT BIOTECHNOLOGY CO., LTD. (CN) | 2015-10-29 | — | — | WO | disclosed |
| US-20150306107-A1 | SAA Derivative Compound Restores eNOS And Inhibits Oxidative Stress-Induced A Diseases In Hypoxia | JANSFAT BIOTECHNOLOGY CO., LTD. (TW) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150306107-A1 | SAA Derivative Compound Restores eNOS And Inhibits Oxidative Stress-Induced A Diseases In Hypoxia | SAAL1, HMOX1, HIF1AN | HTR1A 3142/4885DRD2 3839/4885DRD3 4053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.