SCHEMBL172114

SCHEMBL172114

Cc1c(F)ccc(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.36
HDAC4 P56524 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
DAO P14920 1/20 0.33
NFE2L2 Q16236 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL384037 0.82 ACHE (0.42) ACHEDAONFE2L2
SCHEMBL4549537 0.81 ACHE (0.39) ACHEDAO
SCHEMBL8428973 0.81 ACHE (0.39) ACHEHDAC4CES2CES1
SCHEMBL5399321 0.77 ACHE (0.31) ACHE
SCHEMBL112218 0.77 HDAC4 (0.36) ACHEHDAC4CES2CES1
SCHEMBL23010918 0.77 ACHE (0.31) ACHE
SCHEMBL584965 0.77 KDM1A (0.33) ACHE
SCHEMBL13755137 0.77 ALDH1A1 (0.36) ACHEHDAC4CES2CES1
SCHEMBL13212278 0.77 HDAC4 (0.33) ACHEHDAC4CES2CES1
SCHEMBL12225802 0.77 RAPGEF4 (0.33) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260058204-A1 ELECTROLYTE COMPOSITION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY CONTAINING THE SAME HYUNDAI MOTOR CO LTD (KR) 2026-02-26 US claimed
EP-4273147-A1 SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2023-11-08 EP claimed
CN-116940552-A Spirocyclic hexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors 法国施维雅药厂 2023-10-24 CN claimed
EP-2059516-A1 PYRIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS BIOVITRUM AB (publ) (SE) 2009-05-20 EP claimed
US-20080103123-A1 New compounds BIOVITRUM (SE) 2008-05-01 US claimed
WO-2008025798-A1 PYRIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS BIOVITRUM AB (PUBL) (SE) 2008-03-06 WO claimed
EP-0498724-B1 Esters of 3-(3,3,3-trifluoro-2-chloropropenyl)-2,2-dimethyl-cyclopropanecarboxylic acid, process for their preparation and their use as pesticides ROUSSEL UCLAF (FR) 1996-05-15 EP claimed
EP-4732350-A2 SYSTEMS AND METHODS FOR RECHARGEABLE ENERGY SOURCE SYSTEMS WITH DE-LITHIATED POSITIVE ELECTRODES PURE LITHIUM CORPORATION (US) 2026-04-29 EP disclosed
US-20260058204-A1 ELECTROLYTE COMPOSITION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY CONTAINING THE SAME HYUNDAI MOTOR CO LTD (KR) 2026-02-26 US disclosed
WO-2025231187-A1 LITHIUM METAL ELECTRODE AND BATTERY Pure Lithium Corporation (US) 2025-11-06 WO disclosed
US-20250270725-A1 CROWN ETHER LIQUID-LIQUID EXTRACTION SYSTEM FOR THE ELECTRODEPOSITION OF LITHIUM METAL FROM BRINE Pure Lithium Corporation 2025-08-28 US disclosed
US-12388086-B2 ϵ-VOPO4 cathode for lithium ion batteries THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2025-08-12 US disclosed
EP-4590876-A1 CROWN ETHER LIQUID-LIQUID EXTRACTION SYSTEM FOR THE ELECTRODEPOSITION OF LITHIUM METAL FROM BRINE PURE LITHIUM CORPORATION (US) 2025-07-30 EP disclosed
US-5591744-A 1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLATE DERIVATIVES; MICROBIOCIDES OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1997-01-07 US disclosed
EP-0287951-B1 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents OTSUKA PHARMA CO LTD (JP) 1996-07-03 EP disclosed
US-5495020-A CHEMICAL INTERMEDIATE FOR BACTERICIDES, MICROBIOCIDES, DISINFECTANTS; SIDE EFFECT REDUCTION, ABSORPTION OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1996-02-27 US disclosed
US-5340835-A Insecticides ROUSSEL-UCLAF (FR) 1994-08-23 US disclosed
US-5336670-A 2,2-dimethyl-3-(but-1-en-3-ynyl)-cyclopropane carboxylates ROUSSEL-UCLAF (FR) 1994-08-09 US disclosed
EP-0565132-A2 Benzoheterocyclic compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-10-13 EP disclosed
EP-0287951-A2 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-10-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260058204-A1 ELECTROLYTE COMPOSITION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY CONTAINING THE SAME KCNN2, DYRK1B, SETDB1 ACHE 1953/4885HDAC4 3018/4885CES2 2767/4885
US-20080103123-A1 New compounds GPR119, GPR139, GPR180 ACHE 2534/4885HDAC4 3031/4885CES2 1253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.