Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144695 | 0.81 | ACHE (0.36) | ACHEHDAC4CYP1A2CYP2A6TSHR | |
| SCHEMBL31633781 | 0.81 | ACHE (0.36) | ACHEHDAC4CYP1A2CYP2A6TSHR | |
| SCHEMBL172114 | 0.81 | ACHE (0.36) | ACHEHDAC4CES2CES1 | |
| SCHEMBL13905953 | 0.80 | ACHE (0.38) | ACHECYP1A2CYP2A6TSHRTDP2 | |
| SCHEMBL31633778 | 0.79 | ACHE (0.41) | ACHECYP1A2CYP2A6TSHRTDP2 | |
| SCHEMBL67359 | 0.79 | ACHE (0.41) | ACHEHDAC4CYP1A2CES2CES1 | |
| SCHEMBL3475177 | 0.79 | ACHE (0.41) | ACHECYP1A2CYP2A6TSHRTDP2 | |
| SCHEMBL175646 | 0.79 | ACHE (0.41) | ACHEHDAC4CYP1A2CES2CES1 | |
| SCHEMBL10595967 | 0.78 | ACHE (0.36) | ACHECES2CES1PTGS2PTGS1 | |
| SCHEMBL4549537 | 0.77 | ACHE (0.39) | ACHECYP1A2POLBRAPGEF4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239801-A1 | PYRIMIDO[5,4,D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | Université de Montréal (CA) | 2024-07-18 | — | — | US | disclosed |
| US-20240239801-A1 | PYRIMIDO[5,4,D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | Université de Montréal (CA) | 2024-07-18 | — | — | US | disclosed |
| US-20240217971-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | Université de Montréal (CA) | 2024-07-04 | — | — | US | disclosed |
| US-20240217971-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | Université de Montréal (CA) | 2024-07-04 | — | — | US | disclosed |
| WO-2024077391-A1 | THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | UNIVERSITE DE MONTREAL (CA) | 2024-04-18 | — | — | WO | disclosed |
| US-11916180-B2 | Organic solar cell and photodetector materials and devices | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-02-27 | — | — | US | disclosed |
| US-11916180-B2 | Organic solar cell and photodetector materials and devices | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-02-27 | — | — | US | disclosed |
| US-20230286961-A1 | SUBSTITUTED TETRAHYDROFURANS AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED | 2023-09-14 | — | — | US | disclosed |
| US-20230263056-A1 | ORGANIC SOLAR CELL AND PHOTODETECTOR MATERIALS AND DEVICES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-08-17 | — | — | US | disclosed |
| US-20230227437-A1 | IMMUNOMODULATOR | HITGEN INC (CN) | 2023-07-20 | — | — | US | disclosed |
| US-20090174316-A1 | Novel red electroluminescent compounds and organi electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2009-07-09 | — | — | US | disclosed |
| US-20090145483-A1 | Novel electroluminescent compounds and organic electroluminescent device suing the same | GRACEL DISPLAY INC. (KR) | 2009-06-11 | — | — | US | disclosed |
| EP-2066150-A1 | Novel red electroluminescent compounds and organic electroluminescent device using the same | Gracel Display Inc. (KR) | 2009-06-03 | — | — | EP | disclosed |
| EP-2003131-A1 | AMINOPYRROLIDINE COMPOUND | Taisho Pharmaceutical Co. Ltd. (JP) | 2008-12-17 | — | — | EP | disclosed |
| US-20080193423-A1 | Small organic molecule regulators of cell proliferation | CURIS, INC. (US) | 2008-08-14 | — | — | US | disclosed |
| US-20080058521-A1 | Processes for the preparation of compounds | WYETH (US) | 2008-03-06 | — | — | US | disclosed |
| US-5968868-A | Catalyst for use in the alkylation of isoalkanes | NIPPON OIL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0285324-B1 | PREPARATION OF SUBSTITUTED FLUOROBENZENES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-11-27 | — | — | EP | disclosed |
| EP-0285324-A1 | Preparation of substituted fluorobenzenes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-05 | — | — | EP | disclosed |
| US-4754084-A | PYROLYSIS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286961-A1 | SUBSTITUTED TETRAHYDROFURANS AS MODULATORS OF SODIUM CHANNELS | TRPV1, TRPA1, SCN2B | ACHE 856/4885HDAC4 1029/4885CYP1A2 1919/4885 |
| US-20080193423-A1 | Small organic molecule regulators of cell proliferation | GLI1, SHH, SMO | ACHE 3530/4885HDAC4 1930/4885CYP1A2 4680/4885 |
| US-20090145483-A1 | Novel electroluminescent compounds and organic electroluminescent device suing the same | LEF1, ODC1, AOC2 | ACHE 1498/4885HDAC4 4238/4885CYP1A2 1920/4885 |
| US-20080058521-A1 | Processes for the preparation of compounds | MKI67, MCL1, DCX | ACHE 2596/4885HDAC4 1262/4885CYP1A2 1811/4885 |
| US-20230227437-A1 | IMMUNOMODULATOR | IL17A, IL2, IL2RA | ACHE 4158/4885HDAC4 1719/4885CYP1A2 274/4885 |
| US-20230263056-A1 | ORGANIC SOLAR CELL AND PHOTODETECTOR MATERIALS AND DEVICES | OCIAD1, OCIAD2, CDH1 | ACHE 4455/4885HDAC4 3469/4885CYP1A2 2695/4885 |
| US-20090174316-A1 | Novel red electroluminescent compounds and organi electroluminescent device using the same | ALPI, IK, ALDH1A2 | ACHE 1921/4885HDAC4 4481/4885CYP1A2 2596/4885 |
| US-20240239801-A1 | PYRIMIDO[5,4,D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | NRAS, BRAF, KRAS | ACHE 4868/4885HDAC4 3489/4885CYP1A2 2650/4885 |
| US-11916180-B2 | Organic solar cell and photodetector materials and devices | OCIAD1, OCIAD2, CDH1 | ACHE 4455/4885HDAC4 3469/4885CYP1A2 2695/4885 |
| US-20240217971-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | BRAF, NRAS, DPYD | ACHE 4854/4885HDAC4 3058/4885CYP1A2 2263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.