Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TYMS | P04818 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172120 | 0.83 | ESR1 (0.51) | DHFRESR1ESR2MEN1KMT2A | |
| SCHEMBL217779 | 0.76 | ESR1 (0.65) | DHFRESR1ESR2MEN1KMT2A | |
| SCHEMBL29703330 | 0.76 | ESR1 (0.65) | DHFRESR1ESR2MEN1KMT2A | |
| SCHEMBL16305289 | 0.71 | DHFR (0.74) | DHFRESR1ESR2MEN1KMT2A | |
| SCHEMBL16303133 | 0.71 | DHFR (0.74) | DHFRESR1ESR2MEN1KMT2A | |
| SCHEMBL172119 | 0.69 | ESR2 (0.51) | DHFRESR1ESR2MEN1KMT2A | |
| SCHEMBL172169 | 0.69 | ESR1 (0.77) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL16303136 | 0.69 | LMNA (0.72) | DHFRESR1ESR2MEN1KMT2A | |
| SCHEMBL16303127 | 0.69 | LMNA (0.68) | DHFRESR1ESR2MEN1KMT2A | |
| SCHEMBL16945421 | 0.68 | TDP1 (0.50) | ESR1ESR2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048180-B1 | POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY USING THE SAME | MITSUBISHI GAS CHEMICAL CO (JP) | 2012-03-07 | — | — | EP | disclosed |