SCHEMBL17225992

SCHEMBL17225992

CC1=C2NC(=O)C(C)=C2NC1=O

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
OGT O15294 1/20 0.30
USP2 O75604 1/20 0.30
MAPT P10636 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10830337 0.74 EGFR (0.33) KDM4EOGTUSP2MAPTRECQL
SCHEMBL10830328 0.74 EGFR (0.33) KDM4EOGTUSP2MAPTRECQL
SCHEMBL11375724 0.71 EGFR (0.32) KDM4EOGTUSP2MAPTRECQL
Benzene SCHEMBL29047514 0.69 GSK3B (0.43) KDM4EMAPTBLM
SCHEMBL996564 0.69 PTGS2 (0.33)
SCHEMBL1164153 0.67
SCHEMBL13287284 0.65
SCHEMBL28765079 0.65
SCHEMBL2200799 0.62
SCHEMBL18757806 0.61 CTSD (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170237010-A1 Azinothiadiazole Compounds and Related Semiconductor Devices USINVEST LLC 2017-08-17 US disclosed
US-20170233384-A1 Thienothiadiazole Compounds and Related Semiconductor Devices USINVEST LLC 2017-08-17 US disclosed
US-9711728-B1 Fused thiophene-based conjugated polymers and their use in optoelectronic devices NORTHWESTERN UNIVERSITY (US) 2017-07-18 US disclosed
US-9708346-B2 Semiconducting compounds and related devices FLEXTERRA, INC. (US) 2017-07-18 US disclosed
WO-2017120572-A1 DITHIOPHENETHIADIAZOLE SEMICONDUCTORS AND RELATED DEVICES FLEXTERRA, INC. (US) 2017-07-13 WO disclosed
US-9666805-B2 Bithiophene sulfonamide-based molecular and polymeric semiconductors NORTHWESTERN UNIVERSITY (US) 2017-05-30 US disclosed
US-20170110666-A1 Semiconducting Compounds and Related Devices USINVEST LLC 2017-04-20 US disclosed
US-20170104160-A1 ORGANIC SEMICONDUCTING COMPOUNDS AND RELATED OPTOELECTRONIC DEVICES USINVEST LLC 2017-04-13 US disclosed
US-20170096523-A1 Polymeric Semiconductors and Related Devices USINVEST LLC 2017-04-06 US disclosed
US-20160351815-A1 Phenazine-Based Molecular and Polymeric Semiconductors FLEXTERRA, INC. 2016-12-01 US disclosed
US-20160149138-A1 Bithiophene Sulfonamide-Based Molecular and Polymeric Semiconductors USINVEST LLC 2016-05-26 US disclosed
US-9178160-B1 Fused thiophene-based conjugated polymers and their use in optoelectronic devices NORTHWESTERN UNIVERSITY (US) 2015-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170104160-A1 ORGANIC SEMICONDUCTING COMPOUNDS AND RELATED OPTOELECTRONIC DEVICES AQP4, EPCAM, ORAI2 KDM4E 2494/4885OGT 1998/4885USP2 4670/4885
US-20170110666-A1 Semiconducting Compounds and Related Devices EPCAM, CDH1, BMI1 KDM4E 3059/4885OGT 639/4885USP2 4012/4885
US-20160149138-A1 Bithiophene Sulfonamide-Based Molecular and Polymeric Semiconductors TPST2, TST, SLC43A1 KDM4E 2330/4885OGT 2086/4885USP2 2059/4885
US-20170233384-A1 Thienothiadiazole Compounds and Related Semiconductor Devices TST, SLC19A2, TPST2 KDM4E 3685/4885OGT 1717/4885USP2 4515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.