Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.63 |
| ▸ | RAB9A | P51151 | 9/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.63 |
| ▸ | RELA | Q04206 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6308174 | 1.00 | NPC1 (0.63) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL7739379 | 1.00 | NPC1 (0.63) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL14305656 | 0.80 | HTT (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL16437120 | 0.80 | RAB9A (0.61) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL2954318 | 0.79 | MAPT (0.70) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL11073619 | 0.79 | MAPT (0.70) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL2954324 | 0.79 | MAPT (0.70) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL14305666 | 0.79 | ALDH1A1 (0.67) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL14313167 | 0.79 | NPC1 (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL10966137 | 0.79 | ALDH1A1 (0.67) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411045-B1 | Process for production of optically active amino alcohols | YOKOZAWA TOHRU (JP) | 2008-01-16 | — | — | EP | claimed |
| US-6846957-B2 | Synthesis of 3-aminomethyl-1-propanol, a fluoxetine precursor | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2005-01-25 | — | — | US | claimed |
| US-20040102651-A1 | Synthesis of 3-aminomethyl-1-propanol, a fluoxetine precursor | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2004-05-27 | — | — | US | claimed |
| EP-1411045-B1 | Process for production of optically active amino alcohols | YOKOZAWA TOHRU (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-6984738-B2 | Process for production of optically active amino alcohols | YOKOZAWA TOHRU | 2006-01-10 | — | — | US | disclosed |
| US-6846957-B2 | Synthesis of 3-aminomethyl-1-propanol, a fluoxetine precursor | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2005-01-25 | — | — | US | disclosed |
| US-6846957-B2 | Synthesis of 3-aminomethyl-1-propanol, a fluoxetine precursor | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2005-01-25 | — | — | US | disclosed |
| US-20040102651-A1 | Synthesis of 3-aminomethyl-1-propanol, a fluoxetine precursor | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2004-05-27 | — | — | US | disclosed |
| US-20040082794-A1 | Process for production of optically active amino alcohols | YOKOZAWA TOHRU (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1411045-A1 | Process for production of optically active amino alcohols | Yokozawa, Tohru (JP) | 2004-04-21 | — | — | EP | disclosed |
| EP-1182928-B1 | METHOD FOR PRODUCING MICROBICIDAL SURFACES BY IMMOBILIZING INHERENTLY MICROBICIDALLY ACTIVE MACROMOLECULES | CREAVIS TECH & INNOVATION GMBH (DE) | 2002-11-20 | — | — | EP | disclosed |
| EP-1183291-A1 | ANTIMICROBIAL COPOLYMERS | Creavis Gesellschaft für Technologie und Innovation mbH (DE) | 2002-03-06 | — | — | EP | disclosed |
| EP-1183289-A1 | METHOD FOR PRODUCING INHERENTLY MICROBICIDAL POLYMER SURFACES | Creavis Gesellschaft für Technologie und Innovation mbH (DE) | 2002-03-06 | — | — | EP | disclosed |
| EP-1182928-A1 | METHOD FOR PRODUCING MICROBICIDAL SURFACES BY IMMOBILIZING INHERENTLY MICROBICIDALLY ACTIVE MACROMOLECULES | Creavis Gesellschaft für Technologie und Innovation mbH (DE) | 2002-03-06 | — | — | EP | disclosed |
| EP-1183293-A1 | MICROBICIDAL COPOLYMERS | Creavis Gesellschaft für Technologie und Innovation mbH (DE) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000069936-A1 | ANTIMICROBIAL COPOLYMERS | CREAVIS GESELLSCHAFT FÜR TECHNOLOGIE UND INNOVATION MBH (DE) | 2000-11-23 | — | — | WO | disclosed |
| WO-2000069934-A1 | MICROBICIDAL COPOLYMERS | CREAVIS GESELLSCHAFT FÜR TECHNOLOGIE UND INNOVATION MBH (DE) | 2000-11-23 | — | — | WO | disclosed |
| WO-2000069933-A1 | METHOD FOR PRODUCING INHERENTLY MICROBICIDAL POLYMER SURFACES | CREAVIS GESELLSCHAFT FÜR TECHNOLOGIE UND INNOVATION MBH (DE) | 2000-11-23 | — | — | WO | disclosed |
| WO-2000069264-A1 | METHOD FOR PRODUCING MICROBICIDAL SURFACES BY IMMOBILIZING INHERENTLY MICROBICIDALLY ACTIVE MACROMOLECULES | CREAVIS GESELLSCHAFT FÜR TECHNOLOGIE UND INNOVATION MBH (DE) | 2000-11-23 | — | — | WO | disclosed |
| US-5939436-A | Five-membered heteroaromatic compounds as dopamine receptor subtype ligands | MERCK SHARP & DOHME LTD. (GB) | 1999-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082794-A1 | Process for production of optically active amino alcohols | ADH5, ADH1C, ADH1A | NPC1 4203/4885RAB9A 1255/4885ALDH1A1 122/4885 |
| US-20040102651-A1 | Synthesis of 3-aminomethyl-1-propanol, a fluoxetine precursor | TPH1, HTR1A, TPH2 | NPC1 2642/4885RAB9A 4149/4885ALDH1A1 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.