Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15063962 | 0.82 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL2333762 | 0.80 | PLAU (0.37) | PLAUPDE2AALDH1A1HPGDGLA | |
| SCHEMBL715069 | 0.78 | PLAU (0.36) | PLAUPDE2AALDH1A1HPGDGLA | |
| SCHEMBL17238703 | 0.78 | — | — | |
| SCHEMBL630411 | 0.77 | PLAU (0.35) | PLAUPDE2AALDH1A1HPGDGLA | |
| SCHEMBL19471036 | 0.77 | NOTUM (0.35) | PLAUPDE2AALDH1A1HPGDGLA | |
| SCHEMBL454940 | 0.76 | CES2 (0.35) | — | |
| SCHEMBL17238695 | 0.74 | PDE2A (0.36) | PLAUPDE2AALDH1A1HPGDGLA | |
| SCHEMBL16858738 | 0.72 | KMT2A (0.35) | PLAUPDE2AALDH1A1HPGDKDM4E | |
| SCHEMBL1992298 | 0.72 | GABRB3 (0.38) | PLAUPDE2ASMN1; SMN2GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10435374-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2019-10-08 | — | — | US | disclosed |
| US-20170305864-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-10-26 | — | — | US | disclosed |
| EP-2922831-B1 | PESTICIDAL COMPOUNDS BASED ON ARYLTHIOSULFONAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-18 | — | — | EP | disclosed |
| US-9686988-B2 | Pesticidal compounds based on arylthiosulfonamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2017-06-27 | — | — | US | disclosed |
| US-9675073-B2 | Insecticidal compounds based on N-arylsulfanylmethylcarboxamidearylthiosulfonamides derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2017-06-13 | — | — | US | disclosed |
| US-20160286808-A1 | PESTICIDAL COMPOUNDS BASED ON ARYLTHIOSULFONAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-06 | — | — | US | disclosed |
| US-20150320046-A1 | INSECTICIDAL COMPOUNDS BASED ON N-ARYLSULFANYLMETHYLCARBOXAMIDEARYLTHIOSULFONAMIDES DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10435374-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | PLAU 4408/4885PDE2A 712/4885ALDH1A1 2740/4885 |
| US-20170305864-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | PLAU 4408/4885PDE2A 712/4885ALDH1A1 2740/4885 |
| US-20150320046-A1 | INSECTICIDAL COMPOUNDS BASED ON N-ARYLSULFANYLMETHYLCARBOXAMIDEARYLTHIOSULFONAMIDES DERIVATIVES | C1S, NISCH, ACHE | PLAU 4809/4885PDE2A 750/4885ALDH1A1 564/4885 |
| US-20160286808-A1 | PESTICIDAL COMPOUNDS BASED ON ARYLTHIOSULFONAMIDE DERIVATIVES | ACHE, CHRM2, DDT | PLAU 4846/4885PDE2A 336/4885ALDH1A1 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.