Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.31 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17238705 | 0.80 | PLAU (0.36) | PLAUPDE2AALDH1A1HPGDPOLB | |
| SCHEMBL715069 | 0.80 | PLAU (0.36) | PLAUPDE2AALDH1A1HPGDPOLB | |
| SCHEMBL17434720 | 0.80 | CES2 (0.34) | ALDH1A1HPGDTDP1CYP3A4ALOX15 | |
| SCHEMBL630411 | 0.78 | PLAU (0.35) | PLAUPDE2AALDH1A1HPGDPOLB | |
| SCHEMBL19471036 | 0.78 | NOTUM (0.35) | PLAUPDE2AALDH1A1HPGDPOLB | |
| SCHEMBL17238695 | 0.75 | PDE2A (0.36) | PLAUPDE2AALDH1A1HPGDPOLB | |
| SCHEMBL3411258 | 0.75 | KDM1A (0.38) | PDE2AALDH1A1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL16858738 | 0.74 | KMT2A (0.35) | PLAUPDE2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1992298 | 0.74 | GABRB3 (0.38) | PLAUPDE2ASMN1; SMN2GABRA2GABRB2 | |
| SCHEMBL29052774 | 0.71 | CYP3A4 (0.61) | ALDH1A1HPGDPOLBKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4885027-A | PLANT GROWTH REGULATORS; NONPHYTOTOXIC; PRE- AND POST EMERGENCE | CHEVRON RESEARCH COMPANY (US) | 1989-12-05 | — | — | US | claimed |
| US-4831179-A | HERBICIDES | CHEVRON RESEARCH COMPANY (US) | 1989-05-16 | — | — | US | claimed |
| US-10435374-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2019-10-08 | — | — | US | disclosed |
| EP-3045450-B1 | INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2018-02-07 | — | — | EP | disclosed |
| US-20170305864-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-10-26 | — | — | US | disclosed |
| EP-3045450-A1 | INTERMEDIATE COMPOUNDS IN A PROCESS FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO., LTD. (JP) | 2016-07-20 | — | — | EP | disclosed |
| EP-2614053-B1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATES THEREOF | SUMITOMO CHEMICAL CO (JP) | 2016-03-23 | — | — | EP | disclosed |
| US-8884010-B2 | Method for producing pyridazinone compounds and intermediate thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-11-11 | — | — | US | disclosed |
| US-20130172556-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-04 | — | — | US | disclosed |
| EP-2356101-A1 | PYRIMIDINE AND TRIAZINE SULFONAMIDE DERIVATES AS B1 BRADYKININ RECEPTOR (B1R) INHIBITORS FOR TREATING PAIN | Grünenthal GmbH (DE) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010046109-A1 | PYRIMIDINE AND TRIAZINE SULFONAMIDE DERIVATES AS B1 BRADYKININ RECEPTOR (B1R) INHIBITORS FOR TREATING PAIN | Grünenthal GmbH (DE) | 2010-04-29 | — | — | WO | disclosed |
| US-4885027-A | PLANT GROWTH REGULATORS; NONPHYTOTOXIC; PRE- AND POST EMERGENCE | CHEVRON RESEARCH COMPANY (US) | 1989-12-05 | — | — | US | disclosed |
| US-4831179-A | HERBICIDES | CHEVRON RESEARCH COMPANY (US) | 1989-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10435374-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | PLAU 4408/4885PDE2A 712/4885ALDH1A1 2740/4885 |
| US-20170305864-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | PLAU 4408/4885PDE2A 712/4885ALDH1A1 2740/4885 |
| US-20130172556-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | PDXK, DHPS, NQO1 | PLAU 1745/4885PDE2A 984/4885ALDH1A1 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.