Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 17/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 17/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 17/20 | 0.38 |
| ▸ | GABRP | O00591 | 15/20 | 0.38 |
| ▸ | GABRD | O14764 | 15/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 15/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 15/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 15/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 15/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 15/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 15/20 | 0.38 |
| ▸ | GABRE | P78334 | 15/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 15/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 15/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 15/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 15/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333762 | 0.74 | PLAU (0.37) | GABRA2GABRB2PDE2ARAB9ASMN1; SMN2 | |
| SCHEMBL17238705 | 0.72 | PLAU (0.36) | GABRA2GABRB2PDE2ASMN1; SMN2PLAU | |
| SCHEMBL715069 | 0.72 | PLAU (0.36) | GABRB3GABRA2GABRB2PDE2ARAB9A | |
| SCHEMBL28220138 | 0.71 | ALDH1A1 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL630411 | 0.71 | PLAU (0.35) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL19471036 | 0.71 | NOTUM (0.35) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL16858738 | 0.70 | KMT2A (0.35) | PDE2ARAB9ASMN1; SMN2PLAU | |
| SCHEMBL17238695 | 0.68 | PDE2A (0.36) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6378825 | 0.66 | PDE2A (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL17434720 | 0.64 | CES2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140018377-A1 | Aminopropenoates as Fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-16 | — | — | US | disclosed |
| US-8476197-B2 | Aminopropenoates as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-02 | — | — | US | disclosed |
| US-20110152322-A1 | Aminopropenoates as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152322-A1 | Aminopropenoates as Fungicides | AASDHPPT, DAO, AAAS | GABRB3 257/4885GABRA2 671/4885GABRB2 484/4885 |
| US-20140018377-A1 | Aminopropenoates as Fungicides | ACMSD, AASDHPPT, AAAS | GABRB3 598/4885GABRA2 1369/4885GABRB2 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.