SCHEMBL17239678

SCHEMBL17239678

CC(C)(C)c1cc(P(C(C)(C)C)C(C)(C)C)cc(C(C)(C)C)c1.CC(C)(C)c1cc(P(C(C)(C)C)C(C)(C)C)cc(C(C)(C)C)c1.Cl[Pd]Cl

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
POLB P06746 1/20 0.32
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16694547 0.91 GABRA1 (0.46) GABRA1GABRB2POLBKDM4EGAA
SCHEMBL29670257 0.89 GABRA1 (0.44) GABRA1GABRB2POLBKDM4EGAA
SCHEMBL17239677 0.80 HDAC8 (0.38)
SCHEMBL17239669 0.78 TSHR (0.41) POLBGAAMAPT
SCHEMBL17239683 0.77 ALDH1A1 (0.32) POLB
SCHEMBL2550800 0.73 CES2 (0.38) MAPT
SCHEMBL2225542 0.72 GABRA1 (0.46) GABRA1GABRB2POLBKDM4EGAA
SCHEMBL17239660 0.71 ALDH1A1 (0.44)
SCHEMBL17239666 0.71 HSPA5 (0.31)
SCHEMBL28912676 0.70 GABRA1 (0.44) GABRA1GABRB2POLBKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3037398-B1 METHOD FOR MANUFACTURING CHEMICAL COMPOUND SUMITOMO CHEMICAL CO (JP) 2021-03-10 EP claimed
US-9982087-B2 Method for producing compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-29 US claimed
EP-3037398-B1 METHOD FOR MANUFACTURING CHEMICAL COMPOUND SUMITOMO CHEMICAL CO (JP) 2021-03-10 EP disclosed
US-9982087-B2 Method for producing compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-29 US disclosed
EP-3225610-A1 METHOD FOR MANUFACTURING COMPOUND Sumitomo Chemical Company, Limited (JP) 2017-10-04 EP disclosed
EP-2871198-B1 METHOD FOR PRODUCING AROMATIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-06-14 EP disclosed
US-9453103-B2 Method for producing aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-09-27 US disclosed
US-20160200861-A1 METHOD FOR PRODUCING COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-14 US disclosed
EP-3037398-A1 METHOD FOR MANUFACTURING CHEMICAL COMPOUND Sumitomo Chemical Company, Limited (JP) 2016-06-29 EP disclosed
US-20150322199-A1 METHOD FOR PRODUCING AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150322199-A1 METHOD FOR PRODUCING AROMATIC COMPOUND PAH, DDC, DDT GABRA1 3212/4885GABRB2 3453/4885POLB 1118/4885
US-20160200861-A1 METHOD FOR PRODUCING COMPOUND NUDT1, OSGEP, CNOT9 GABRA1 2769/4885GABRB2 2410/4885POLB 26/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.