Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29611269 | 1.00 | ESR2 (0.46) | ESR2APPCYP3A4CYP2C9CYP2D6 | |
| SCHEMBL26167206 | 0.92 | CYP3A4 (0.38) | ESR2APPCYP3A4CYP2C9CYP2D6 | |
| SCHEMBL26672922 | 0.88 | CYP3A4 (0.36) | ESR2APPCYP3A4CYP2C9CYP2D6 | |
| SCHEMBL802765 | 0.86 | ESR2 (0.46) | ESR2APPCYP3A4CYP2C9CYP2D6 | |
| SCHEMBL16769002 | 0.86 | CYP3A4 (0.42) | ESR2APPCYP3A4CYP2C9CYP2D6 | |
| SCHEMBL16768999 | 0.86 | CYP3A4 (0.45) | APPCYP3A4CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL18251036 | 0.85 | SPHK1 (0.39) | ESR2APPCYP3A4CYP2C9CYP2D6 | |
| SCHEMBL15445840 | 0.85 | ESR2 (0.45) | ESR2APPCYP3A4CYP2C9CYP2D6 | |
| SCHEMBL12658807 | 0.85 | ESR2 (0.45) | ESR2APPCYP3A4CYP2C9CYP2D6 | |
| SCHEMBL24778682 | 0.84 | CYP3A4 (0.47) | APPCYP3A4CYP2C9DGAT1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399281-A1 | METHOD FOR PERFORMING MITSUNOBU REACTION BETWEEN ALCOHOLIC HYDROXYL GROUP DONOR AND ACTIVE HYDROGEN DONOR | JIANGSU HECHENG ADVANCED MATERIALS CO., LTD. (CN) | 2023-12-14 | — | — | US | disclosed |
| US-20230399281-A1 | METHOD FOR PERFORMING MITSUNOBU REACTION BETWEEN ALCOHOLIC HYDROXYL GROUP DONOR AND ACTIVE HYDROGEN DONOR | JIANGSU HECHENG ADVANCED MATERIALS CO., LTD. (CN) | 2023-12-14 | — | — | US | disclosed |
| US-20230399281-A1 | METHOD FOR PERFORMING MITSUNOBU REACTION BETWEEN ALCOHOLIC HYDROXYL GROUP DONOR AND ACTIVE HYDROGEN DONOR | JIANGSU HECHENG ADVANCED MATERIALS CO., LTD. (CN) | 2023-12-14 | — | — | US | disclosed |
| WO-2022088244-A1 | METHOD FOR PERFORMING MITSUNOBU REACTION BETWEEN ALCOHOLIC HYDROXYL GROUP DONOR AND ACTIVE HYDROGEN DONOR | 江苏和成新材料有限公司 | 2022-05-05 | — | — | WO | disclosed |
| EP-1763569-B1 | LIQUID CRYSTAL MEDIUM AND ELECTROOPTICAL DISPLAY CONTAINING SAME | MERCK PATENT GMBH (DE) | 2018-01-17 | — | — | EP | disclosed |
| US-20170088776-A1 | LIQUID CRYSTAL MEDIUM AND ELECTROOPTICAL DISPLAY CONTAINING SAME | MERCK PATENT GMBH (DE) | 2017-03-30 | — | — | US | disclosed |
| US-9550942-B2 | Liquid crystal medium and electrooptical display containing same | MERCK PATENT GMBH (DE) | 2017-01-24 | — | — | US | disclosed |
| US-20120307177-A1 | LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-06 | — | — | US | disclosed |
| EP-2199362-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2012-08-29 | — | — | EP | disclosed |
| EP-2265691-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-08-29 | — | — | EP | disclosed |
| WO-2010057575-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2010-05-27 | — | — | WO | disclosed |
| US-20100108945-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-05-06 | — | — | US | disclosed |
| EP-2182046-A1 | Liquid-crystalline medium and liquid crystal display | Merck Patent GmbH (DE) | 2010-05-05 | — | — | EP | disclosed |
| US-20090309066-A1 | Mixture of polar compounds containing cyclohexane and benzene rings some of which are vinylene-linked, especially containing fluoroalkoxy groups; for electrooptical twisted nematic monitor applications | MERCK PATENT GESELLSCHAFT (DE) | 2009-12-17 | — | — | US | disclosed |
| WO-2009129911-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH, (DE) | 2009-10-29 | — | — | WO | disclosed |
| WO-2009115186-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2009-09-24 | — | — | WO | disclosed |
| US-20090213318-A1 | Liquid crystal medium and electrooptical display containing same | MERCK PATENT GESELLSCHAFT (DE) | 2009-08-27 | — | — | US | disclosed |
| US-20080149891-A1 | STILBENE DERIVATIVES, LIQUID-CRYSTAL MIXTURES AND ELECTRO-OPTICAL DISPLAYS | MERCK PATENT GESELLSCHAFT (DE) | 2008-06-26 | — | — | US | disclosed |
| EP-1932896-A1 | Stilbene derivatives, liquid-crystal mixtures and electro-optical displays | MERCK PATENT GmbH (DE) | 2008-06-18 | — | — | EP | disclosed |
| WO-2008009417-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080149891-A1 | STILBENE DERIVATIVES, LIQUID-CRYSTAL MIXTURES AND ELECTRO-OPTICAL DISPLAYS | SBDS, LSS, VCL | ESR2 1012/4885APP 2371/4885CYP3A4 1126/4885 |
| US-20230399281-A1 | METHOD FOR PERFORMING MITSUNOBU REACTION BETWEEN ALCOHOLIC HYDROXYL GROUP DONOR AND ACTIVE HYDROGEN DONOR | ADH5, ADH1C, ADH1A | ESR2 3431/4885APP 4133/4885CYP3A4 112/4885 |
| US-20120307177-A1 | LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTALLINE MEDIUM | CUTA, NEFM, FES | ESR2 1269/4885APP 216/4885CYP3A4 2439/4885 |
| US-20090309066-A1 | Mixture of polar compounds containing cyclohexane and benzene rings some of which are vinylene-linked, especially containing fluoroalkoxy groups; for electrooptical twisted nematic monitor applications | VIM, CDH1, LEF1 | ESR2 1692/4885APP 2124/4885CYP3A4 3869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.