SCHEMBL17248264

SCHEMBL17248264

c1ccc(-c2cccc(-n3c4ccccc4c4c5c6ccccc6n(-c6nc(-c7ccccc7)cc(-c7ccccc7)n6)c5ccc43)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.39
KDM4E B2RXH2 2/20 0.39
ATM Q13315 2/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
GABRA5 P31644 2/20 0.39
GABRA3 P34903 2/20 0.39
PDE10A Q9Y233 1/20 0.35
MAPT P10636 3/20 0.35
MAPK1 P28482 3/20 0.35
NPSR1 Q6W5P4 3/20 0.35
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
ALDH1A1 P00352 3/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GAA P10253 2/20 0.34
TET2 Q6N021 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23805774 0.99 L3MBTL1 (0.38) L3MBTL1KDM4EATMGABRG2GABRB3
SCHEMBL23184198 0.95 L3MBTL1 (0.39) L3MBTL1KDM4EATMGABRG2GABRB3
SCHEMBL23183657 0.94 L3MBTL1 (0.38) L3MBTL1KDM4EATMGABRG2GABRB3
SCHEMBL23184816 0.94 GABRG2 (0.35) L3MBTL1KDM4EATMGABRG2GABRB3
SCHEMBL23183712 0.94 L3MBTL1 (0.38) L3MBTL1KDM4EATMGABRG2GABRB3
SCHEMBL20152221 0.94 MEN1 (0.40) L3MBTL1KDM4EATMGABRG2GABRB3
SCHEMBL19769790 0.94 L3MBTL1 (0.41) L3MBTL1KDM4EATMGABRG2GABRB3
SCHEMBL23805832 0.94 L3MBTL1 (0.44) L3MBTL1KDM4EATMGABRG2GABRB3
SCHEMBL23184817 0.93 GABRG2 (0.34) L3MBTL1KDM4EATMGABRG2GABRB3
SCHEMBL23183654 0.93 L3MBTL1 (0.37) L3MBTL1KDM4EATMGABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702420-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-18 US disclosed
US-11702420-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-18 US disclosed
US-20210323968-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-10-21 US disclosed
US-11117897-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-09-14 US disclosed
US-10361378-B2 Organic electroluminescent device NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2019-07-23 US disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11117897-B2 Organic electroluminescent materials and devices ECI1, NDUFS3, NDUFV1 L3MBTL1 2949/4885KDM4E 3164/4885ATM 2475/4885
US-11702420-B2 Organic electroluminescent materials and devices ECI1, NDUFS3, NDUFV1 L3MBTL1 2949/4885KDM4E 3164/4885ATM 2475/4885
US-10361378-B2 Organic electroluminescent device ELF3, DDT, LEF1 L3MBTL1 74/4885KDM4E 1228/4885ATM 3768/4885
US-20210323968-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ECI1, NDUFS3, NDUFV1 L3MBTL1 2949/4885KDM4E 3164/4885ATM 2475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.