SCHEMBL17248339

SCHEMBL17248339

c1ccc2c(c1)oc1c(-c3ccc4c(c3)c3ccccc3n4-c3cccc4c3oc3ccccc34)cccc12

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.54
PRKDC P78527 7/20 0.46
GGPS1 O95749 1/20 0.44
PTGES2 Q9H7Z7 1/20 0.39
ATM Q13315 1/20 0.37
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
PIK3CD O00329 1/20 0.35
PIK3CB P42338 1/20 0.35
AHR P35869 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MEN1 O00255 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
HDAC8 Q9BY41 1/20 0.31
TSPO P30536 1/20 0.31
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5028287 0.99 ALOX5 (0.53) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL13830071 0.96 ALOX5 (0.56) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL15630572 0.96 ALOX5 (0.56) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL13829522 0.95 ALOX5 (0.54) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL22106831 0.95 ALOX5 (0.54) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL22106837 0.93 ALOX5 (0.48) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL26530238 0.92 ALOX5 (0.54) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL5029690 0.92 ALOX5 (0.47) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL14849210 0.92 ALOX5 (0.47) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL10092199 0.92 ALOX5 (0.47) ALOX5PRKDCGGPS1PTGES2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11358951-B2 Π(PI)-conjugated compound, organic electroluminescence element material, light-emitting material, light-emitting thin film, organic electroluminescence element, display device, and illumination device MERCK PATENT GMBH (DE) 2022-06-14 US disclosed
US-11075343-B2 Organic light emitting compounds and organic light emitting devices including the same SFC CO., LTD. (KR) 2021-07-27 US disclosed
US-10361378-B2 Organic electroluminescent device NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2019-07-23 US disclosed
US-20180170914-A1 II(PI)-CONJUGATED COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, LIGHT-EMITTING MATERIAL, LIGHT-EMITTING THIN FILM, ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, AND ILLUMINATION DEVICE Konica Minolta, Inc. (JP) 2018-06-21 US disclosed
US-20180170914-A1 II(PI)-CONJUGATED COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, LIGHT-EMITTING MATERIAL, LIGHT-EMITTING THIN FILM, ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, AND ILLUMINATION DEVICE Konica Minolta, Inc. (JP) 2018-06-21 US disclosed
US-9911924-B2 Material for organic optoelectronic device, organic light emitting diode including the same, and display including the organic light emitting diode SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-03-06 US disclosed
US-9911924-B2 Material for organic optoelectronic device, organic light emitting diode including the same, and display including the organic light emitting diode SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-03-06 US disclosed
US-20170207397-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME SFC CO., LTD. (KR) 2017-07-20 US disclosed
US-20170207397-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME SFC CO., LTD. (KR) 2017-07-20 US disclosed
EP-2933851-B1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL & SUMIKIN CHEM CO (JP) 2017-05-10 EP disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11075343-B2 Organic light emitting compounds and organic light emitting devices including the same HARS1, ALDH1A2, NR2E3 ALOX5 1194/4885PRKDC 4712/4885GGPS1 2282/4885
US-20180170914-A1 II(PI)-CONJUGATED COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, LIGHT-EMITTING MATERIAL, LIGHT-EMITTING THIN FILM, ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, AND ILLUMINATION DEVICE OCIAD2, ZYX, OCIAD1 ALOX5 1480/4885PRKDC 3782/4885GGPS1 1915/4885
US-10361378-B2 Organic electroluminescent device ELF3, DDT, LEF1 ALOX5 1717/4885PRKDC 1748/4885GGPS1 2388/4885
US-20170207397-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME HARS1, ALDH1A2, ALDH1A3 ALOX5 1196/4885PRKDC 4611/4885GGPS1 1850/4885
US-11358951-B2 Π(PI)-conjugated compound, organic electroluminescence element material, light-emitting material, light-emitting thin film, organic electroluminescence element, display device, and illumination device ZYX, OCIAD2, DRD1 ALOX5 1572/4885PRKDC 3866/4885GGPS1 1414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.