Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16330891 | 0.72 | CYP2C9 (0.36) | SMN1; SMN2CYP2C9KMT2ATSHRMEN1 | |
| SCHEMBL2510446 | 0.69 | IDO1 (0.42) | SMN1; SMN2CYP2C9KMT2ATSHRAKR1C3 | |
| SCHEMBL2802546 | 0.69 | MYC (0.53) | KMT2AMEN1 | |
| SCHEMBL15754580 | 0.68 | ALDH1A1 (0.54) | CYP2C9AKR1C3AKR1C1 | |
| SCHEMBL1367745 | 0.68 | MARS1 (0.44) | KMT2ATSHRMEN1 | |
| SCHEMBL1063920 | 0.67 | CYP2C9 (0.61) | SMN1; SMN2CYP2C9KMT2ATSHRHCAR2 | |
| SCHEMBL3383807 | 0.67 | ALDH1A1 (0.45) | CYP2C9AKR1C3AKR1C1 | |
| SCHEMBL25280786 | 0.66 | HTT (0.49) | SMN1; SMN2TSHR | |
| SCHEMBL10581947 | 0.66 | RPA1 (0.55) | SMN1; SMN2TSHR | |
| SCHEMBL8297949 | 0.66 | NPC1 (0.49) | TSHRAKR1C3AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9475777-B2 | Thermally robust, highly porous, and partially fluorinated organic framework with affinity for hydrocarbons, fluorocarbons and freons | UNIVERSITY OF HOUSTON SYSTEM (US) | 2016-10-25 | — | — | US | disclosed |
| CN-105579127-A | Aldehyde removal material | TOYO BOSEKI | 2016-05-11 | — | — | CN | disclosed |
| US-20150329492-A1 | THERMALLY ROBUST, HIGHLY POROUS, AND PARTIALLY FLUORINATED ORGANIC FRAMEWORK WITH AFFINITY FOR HYDROCARBONS, FLUOROCARBONS AND FREONS | UNIVERSITY OF HOUSTON SYSTEM (US) | 2015-11-19 | — | — | US | disclosed |
| WO-2015175348-A1 | THERMALLY ROBUST, HIGHLY POROUS, AND PARTIALLY FLUORINATED ORGANIC FRAMEWORK WITH AFFINITY FOR HYDROCARBONS, FLUOROCARBONS AND FREONS | UNIVERSITY OF HOUSTON SYSTEM (US) | 2015-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329492-A1 | THERMALLY ROBUST, HIGHLY POROUS, AND PARTIALLY FLUORINATED ORGANIC FRAMEWORK WITH AFFINITY FOR HYDROCARBONS, FLUOROCARBONS AND FREONS | FPR1, FPR3, FPR2 | SMN1; SMN2 4496/4885CYP2C9 410/4885KMT2A 2498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.