Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 3/20 | 0.33 |
| ▸ | YTHDF3 | Q7Z739 | 1/20 | 0.31 |
| ▸ | YTHDF1 | Q9BYJ9 | 1/20 | 0.31 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5763194 | 0.92 | PDE5A (0.39) | ALDH1A1CYP2C9HPGDGAAMAPT | |
| SCHEMBL13455320 | 0.90 | PDE5A (0.41) | ALDH1A1CYP2C9HPGDGAAMAPT | |
| SCHEMBL22077239 | 0.83 | LMNA (0.36) | ALDH1A1YTHDF3YTHDF1YTHDF2PDE5A | |
| SCHEMBL1789261 | 0.63 | ATM (0.50) | ALDH1A1GAAMAPTKDM4ENPSR1 | |
| SCHEMBL3384992 | 0.61 | KDM3B (0.44) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL16661295 | 0.61 | CSNK1A1 (0.33) | ALDH1A1HPGDMAPT | |
| SCHEMBL18552741 | 0.61 | ALDH1A1 (0.32) | ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL5793071 | 0.60 | MAPT (0.56) | ALDH1A1CYP2C9HPGDGAAMAPT | |
| SCHEMBL11633136 | 0.60 | ALDH1A1 (0.50) | ALDH1A1CYP2C9HPGDGAAMAPT | |
| SCHEMBL17285532 | 0.60 | MAPT (0.40) | ALDH1A1CYP2C9HPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3661932-B1 | COMPOSITIONS AND METHODS FOR STABILIZING BENZOTHIAZOLE LUCIFERIN ANALOGS | PROMEGA CORP (US) | 2021-10-06 | — | — | EP | claimed |
| US-11136615-B2 | Compositions and methods for stabilizing benzothiazole luciferin analogs | PROMEGA CORPORATION (US) | 2021-10-05 | — | — | US | claimed |
| EP-3661932-A1 | COMPOSITIONS AND METHODS FOR STABILIZING BENZOTHIAZOLE LUCIFERIN ANALOGS | Promega Corporation (US) | 2020-06-10 | — | — | EP | claimed |
| WO-2019028272-A1 | COMPOSITIONS AND METHODS FOR STABILIZING BENZOTHIAZOLE LUCIFERIN ANALOGS | PROMEGA CORPORATION (US) | 2019-02-07 | — | — | WO | claimed |
| US-20190040449-A1 | COMPOSITIONS AND METHODS FOR STABILIZING BENZOTHIAZOLE LUCIFERIN ANALOGS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2019-02-07 | — | — | US | claimed |
| EP-3146066-B1 | COMPOSITIONS AND METHODS FOR STABILIZING LUMINOGENIC SUBSTRATES | PROMEGA CORP (US) | 2018-03-14 | — | — | EP | claimed |
| US-9676997-B2 | Compositions and methods for stabilizing luminogenic substrates | PROMEGA CORPORATION (US) | 2017-06-13 | — | — | US | claimed |
| EP-3146066-A1 | COMPOSITIONS AND METHODS FOR STABILIZING LUMINOGENIC SUBSTRATES | Promega Corporation (US) | 2017-03-29 | — | — | EP | claimed |
| US-20150337198-A1 | COMPOSITIONS AND METHODS FOR STABILIZING LUMINOGENIC SUBSTRATES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2015-11-26 | — | — | US | claimed |
| WO-2015179864-A1 | COMPOSITIONS AND METHODS FOR STABILIZING LUMINOGENIC SUBSTRATES | PROMEGA CORPORATION (US) | 2015-11-26 | — | — | WO | claimed |
| US-20250264464-A1 | COMPOSITIONS AND METHODS FOR ANALYTE DETECTION USING BIOLUMINESCENCE | PROMEGA CORPORATION | 2025-08-21 | — | — | US | disclosed |
| EP-3661932-B1 | COMPOSITIONS AND METHODS FOR STABILIZING BENZOTHIAZOLE LUCIFERIN ANALOGS | PROMEGA CORP (US) | 2021-10-06 | — | — | EP | disclosed |
| EP-3661932-B1 | COMPOSITIONS AND METHODS FOR STABILIZING BENZOTHIAZOLE LUCIFERIN ANALOGS | PROMEGA CORP (US) | 2021-10-06 | — | — | EP | disclosed |
| US-11136615-B2 | Compositions and methods for stabilizing benzothiazole luciferin analogs | PROMEGA CORPORATION (US) | 2021-10-05 | — | — | US | disclosed |
| US-11136615-B2 | Compositions and methods for stabilizing benzothiazole luciferin analogs | PROMEGA CORPORATION (US) | 2021-10-05 | — | — | US | disclosed |
| EP-3146066-A1 | COMPOSITIONS AND METHODS FOR STABILIZING LUMINOGENIC SUBSTRATES | Promega Corporation (US) | 2017-03-29 | — | — | EP | disclosed |
| WO-2015179864-A1 | COMPOSITIONS AND METHODS FOR STABILIZING LUMINOGENIC SUBSTRATES | PROMEGA CORPORATION (US) | 2015-11-26 | — | — | WO | disclosed |
| WO-2015179864-A1 | COMPOSITIONS AND METHODS FOR STABILIZING LUMINOGENIC SUBSTRATES | PROMEGA CORPORATION (US) | 2015-11-26 | — | — | WO | disclosed |
| US-20150337198-A1 | COMPOSITIONS AND METHODS FOR STABILIZING LUMINOGENIC SUBSTRATES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2015-11-26 | — | — | US | disclosed |
| US-20150337198-A1 | COMPOSITIONS AND METHODS FOR STABILIZING LUMINOGENIC SUBSTRATES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040449-A1 | COMPOSITIONS AND METHODS FOR STABILIZING BENZOTHIAZOLE LUCIFERIN ANALOGS | TK1, TYMP, NUDT1 | ALDH1A1 2006/4885CYP2C9 2452/4885HPGD 2221/4885 |
| US-11136615-B2 | Compositions and methods for stabilizing benzothiazole luciferin analogs | TK1, TYMP, NUDT1 | ALDH1A1 2006/4885CYP2C9 2452/4885HPGD 2221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.