Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 7/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 7/20 | 0.43 |
| ▸ | ITGAL | P20701 | 7/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.42 |
| ▸ | CKS1B | P61024 | 4/20 | 0.41 |
| ▸ | SKP1 | P63208 | 4/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 4/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728042 | 0.87 | RXRA (0.46) | RXRAITGB2ICAM1ITGALCHRM4 | |
| SCHEMBL1727922 | 0.87 | DRD2 (0.46) | CHRM4 | |
| SCHEMBL1729260 | 0.84 | HTR3A (0.42) | CHRM4CKS1BSKP1SKP2 | |
| SCHEMBL1727927 | 0.80 | HRH4 (0.44) | — | |
| SCHEMBL1730192 | 0.80 | CKS1B (0.46) | CKS1BSKP1SKP2 | |
| SCHEMBL1728164 | 0.80 | KDM4E (0.45) | — | |
| SCHEMBL1727727 | 0.79 | MAP4K4 (0.40) | CKS1BSKP1SKP2 | |
| SCHEMBL1730154 | 0.79 | DRD2 (0.42) | — | |
| SCHEMBL1727560 | 0.79 | KCNH2 (0.42) | CHRM4CKS1BSKP1SKP2MCHR1 | |
| SCHEMBL1728883 | 0.79 | MAP4K4 (0.44) | CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |