Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | ACACB | O00763 | 6/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 3/20 | 0.32 |
| ▸ | SKP1 | P63208 | 3/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | DNM1L | O00429 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728808 | 0.90 | PKM (0.37) | HRH3ACACBTRPV3CKS1BSKP1 | |
| SCHEMBL1727724 | 0.88 | HSD11B1 (0.40) | HRH3ACACBTRPV3FFAR4CKS1B | |
| SCHEMBL1728682 | 0.87 | ACACB (0.40) | ACACBHTR1ACKS1BSKP1SKP2 | |
| SCHEMBL1727875 | 0.85 | ACACB (0.40) | HRH3ACACBFFAR4CKS1BSKP1 | |
| SCHEMBL1727921 | 0.82 | KDM4E (0.43) | HRH3HTR1A | |
| SCHEMBL1727577 | 0.82 | PANK3 (0.38) | HRH3 | |
| SCHEMBL1728165 | 0.81 | KDM4E (0.45) | HRH3 | |
| SCHEMBL1729592 | 0.80 | PTGES (0.42) | HSD11B1 | |
| SCHEMBL1727648 | 0.80 | MAPT (0.34) | — | |
| SCHEMBL1730195 | 0.80 | HCAR2 (0.46) | CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |