Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 7/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | USP9X | Q93008 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727892 | 0.88 | HTR1A (0.39) | SMO | |
| SCHEMBL1728232 | 0.86 | PTGES (0.41) | PTGESPDE10AFAAHSMOMAP4K4 | |
| SCHEMBL1728165 | 0.85 | KDM4E (0.45) | PDE10APDE2A | |
| SCHEMBL1727724 | 0.84 | HSD11B1 (0.40) | HSD11B1 | |
| SCHEMBL1729370 | 0.84 | HRH3 (0.43) | PTGESPDE10ASMOPDE2AHSD11B1 | |
| SCHEMBL1728682 | 0.83 | ACACB (0.40) | PDE10A | |
| SCHEMBL1729308 | 0.82 | HRH3 (0.44) | PDE10AFAAHPDE2A | |
| SCHEMBL1727875 | 0.82 | ACACB (0.40) | HSD11B1 | |
| SCHEMBL1728808 | 0.81 | PKM (0.37) | PDE10A | |
| SCHEMBL1727648 | 0.81 | MAPT (0.34) | PDE10APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |