Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 15/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727891 | 0.78 | ALDH1A1 (0.43) | MAPT | |
| SCHEMBL1727831 | 0.75 | FAAH (0.47) | RAB9ANPC1POLBMAPTMAPK1 | |
| SCHEMBL1727884 | 0.74 | HTR1A (0.44) | MAPTMAPK1 | |
| SCHEMBL1729007 | 0.74 | PKM (0.47) | — | |
| SCHEMBL1729369 | 0.72 | MAPT (0.46) | POLBMAPTMAPK1 | |
| SCHEMBL1727873 | 0.70 | FAAH (0.53) | RAB9ANPC1POLBMAPTMAPK1 | |
| SCHEMBL1729364 | 0.69 | KMT2A (0.50) | RAB9ANPC1POLBMAPTCNR2 | |
| SCHEMBL2757296 | 0.67 | RAB9A (0.45) | RAB9ANPC1POLBMAPTMAPK1 | |
| SCHEMBL3763277 | 0.66 | FAAH (0.73) | RAB9ANPC1FAAH | |
| SCHEMBL3004397 | 0.65 | FAAH (0.91) | POLBMAPTMAPK1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |