Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729364 | 0.78 | KMT2A (0.50) | PKMKDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1729003 | 0.75 | PKM (0.48) | PKMKDM4EKMT2ASLC6A7CA12 | |
| SCHEMBL1727891 | 0.75 | ALDH1A1 (0.43) | KDM4EKMT2AADRB1ALDH1A1 | |
| SCHEMBL1727832 | 0.74 | RAB9A (0.45) | — | |
| SCHEMBL1729369 | 0.74 | MAPT (0.46) | PKMKDM4EKMT2AALDH1A1 | |
| SCHEMBL1727884 | 0.71 | HTR1A (0.44) | KDM4EKMT2AADRB1ALDH1A1TDP1 | |
| SCHEMBL1729313 | 0.71 | PKM (0.55) | PKMKDM4EKMT2ASLC6A7CA12 | |
| SCHEMBL28070992 | 0.69 | ADRB1 (0.73) | PKMKDM4EKMT2ASLC6A7CA12 | |
| SCHEMBL3069202 | 0.69 | PKM (0.77) | PKMKDM4EKMT2ASLC6A7CA12 | |
| SCHEMBL16480406 | 0.67 | HDAC6 (0.51) | PKMKDM4ESLC6A7CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |