SCHEMBL17278565

SCHEMBL17278565

CC(C)(C)c1ccc(-c2nc(-c3ccc(N4c5ccccc5C(C)(C)c5ccccc54)cc3)nc(-c3ccc(C(C)(C)C)cc3)n2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 4/20 0.42
▸ NPC1 O15118 3/20 0.42
▸ TP53 P04637 4/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ MEN1 O00255 2/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ ABCG2 Q9UNQ0 1/20 0.35
▸ S1PR1 P21453 1/20 0.35
▸ HDAC6 Q9UBN7 1/20 0.34
▸ TNF P01375 1/20 0.34
▸ NOD1 Q9Y239 1/20 0.34
▸ LMNA P02545 2/20 0.33
▸ MAPT P10636 2/20 0.33
▸ HPGD P15428 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ XDH P47989 1/20 0.33
▸ P2RY1 P47900 1/20 0.33
▸ AKT1 P31749 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17278593 0.90 KMT2A (0.36) MEN1KMT2ALMNAMAPTHPGD
SCHEMBL15046109 0.89 P2RY1 (0.38) TP53KMT2ALMNATSHRHTT
SCHEMBL17278591 0.87 L3MBTL1 (0.42) RAB9ANPC1MEN1KMT2ALMNA
SCHEMBL29397786 0.87 L3MBTL1 (0.42) RAB9ANPC1MEN1KMT2ALMNA
SCHEMBL17278546 0.87 L3MBTL1 (0.42) RAB9ANPC1MEN1KMT2ALMNA
SCHEMBL17278548 0.86 L3MBTL1 (0.41) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL17278553 0.86 L3MBTL1 (0.41) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL17278547 0.86 L3MBTL1 (0.41) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL17278590 0.86 L3MBTL1 (0.41) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL17278577 0.86 TP53 (0.37) RAB9ANPC1TP53SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 — — US disclosed
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 — — US disclosed
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-04-11 — — US disclosed
US-10186665-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-01-22 — — US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 — — US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 — — US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 — — US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 — — US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 — — US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 — — US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 — — US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT TCF4, TRPA1, EML4 RAB9A 1741/4885NPC1 2912/4885TP53 2404/4885
US-11730052-B2 Light-emitting device GRK7, GRK1, CTNND1 RAB9A 808/4885NPC1 2689/4885TP53 4105/4885
US-10186665-B2 Organic electroluminescent element TCF4, TRPA1, EML4 RAB9A 1741/4885NPC1 2912/4885TP53 2404/4885
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AOC2, AZI2, RER1 RAB9A 2437/4885NPC1 1304/4885TP53 4159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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