SCHEMBL17278671

SCHEMBL17278671

CC1(C)c2ccccc2N(c2ccc(-c3nc(-c4ccccc4)nc(-c4ccc(N5c6ccccc6Sc6ccccc65)cc4)n3)cc2)c2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ HDAC6 Q9UBN7 1/20 0.42
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ MAOA P21397 1/20 0.35
▸ ADAMTS5 Q9UNA0 1/20 0.34
▸ BCHE P06276 3/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ ACHE P22303 1/20 0.33
▸ EGLN1 Q9GZT9 2/20 0.32
▸ MARK4 Q96L34 1/20 0.32
▸ MAPT P10636 2/20 0.32
▸ NOX1 Q9Y5S8 2/20 0.32
▸ PDE6D O43924 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ MEN1 O00255 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17278675 0.99 HDAC6 (0.41) HDAC6L3MBTL1MAOAADAMTS5BCHE
SCHEMBL17278706 0.97 HDAC6 (0.44) HDAC6L3MBTL1MAOAADAMTS5BCHE
SCHEMBL17278703 0.97 HDAC6 (0.44) HDAC6L3MBTL1MAOAADAMTS5BCHE
SCHEMBL17278646 0.94 HDAC6 (0.38) HDAC6L3MBTL1MAOAADAMTS5BCHE
SCHEMBL17278589 0.94 HDAC6 (0.38) HDAC6L3MBTL1MAOAADAMTS5BCHE
SCHEMBL17278644 0.91 HDAC6 (0.36) HDAC6L3MBTL1ADAMTS5MARK4MAPT
SCHEMBL17278579 0.91 HDAC6 (0.36) HDAC6L3MBTL1ADAMTS5MARK4MAPT
SCHEMBL17278591 0.91 L3MBTL1 (0.42) L3MBTL1ADAMTS5KDM4EEGLN1MAPT
SCHEMBL17278546 0.91 L3MBTL1 (0.42) L3MBTL1ADAMTS5KDM4EEGLN1MAPT
SCHEMBL29397786 0.91 L3MBTL1 (0.42) L3MBTL1ADAMTS5KDM4EEGLN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 — — US disclosed
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 — — US disclosed
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-04-11 — — US disclosed
US-10186665-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-01-22 — — US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 — — US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 — — US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 — — US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 — — US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 — — US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 — — US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 — — US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT TCF4, TRPA1, EML4 HDAC6 3505/4885L3MBTL1 737/4885MAOA 1482/4885
US-11730052-B2 Light-emitting device GRK7, GRK1, CTNND1 HDAC6 4858/4885L3MBTL1 566/4885MAOA 2598/4885
US-10186665-B2 Organic electroluminescent element TCF4, TRPA1, EML4 HDAC6 3505/4885L3MBTL1 737/4885MAOA 1482/4885
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AOC2, AZI2, RER1 HDAC6 3806/4885L3MBTL1 2484/4885MAOA 641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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