Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | LCAT | P04180 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729688 | 0.85 | LMNA (0.59) | CHRM4DPP4DPP7CHRM2CHRM1 | |
| SCHEMBL1728042 | 0.84 | RXRA (0.46) | CHRM4OPRD1USP30 | |
| SCHEMBL1729365 | 0.82 | NOTUM (0.52) | CHRM4HRH3MAPTALDH1A1LMNA | |
| SCHEMBL1729202 | 0.80 | KDM4E (0.46) | DPP4DPP7MAPTKDM4EALDH1A1 | |
| SCHEMBL1730249 | 0.79 | HTR3A (0.42) | CHRM4LMNADGAT1 | |
| SCHEMBL1728821 | 0.77 | CHRM4 (0.68) | FFAR4CHRM4FFAR1DPP4DPP7 | |
| SCHEMBL1730190 | 0.76 | CHRM4 (0.44) | CHRM4KDM4EALDH1A1PPARGPPARD | |
| SCHEMBL1730164 | 0.76 | DEGS1 (0.47) | CHRM4MAPTKDM4EPPARGPPARD | |
| SCHEMBL1729770 | 0.76 | LMNA (0.38) | CHRM4LMNAACACBDGAT1 | |
| SCHEMBL1730301 | 0.76 | LMNA (0.38) | CHRM4KDM4EABL1LMNADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |