Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728019 | 0.83 | FFAR4 (0.36) | — | |
| SCHEMBL1730190 | 0.81 | CHRM4 (0.44) | KDM4EALDH1A1LMNA | |
| SCHEMBL1730164 | 0.81 | DEGS1 (0.47) | KDM4EGPR119MAPTLMNADRD2 | |
| SCHEMBL1728015 | 0.80 | FFAR4 (0.52) | KDM4EMAPTDPP4DPP7ALDH1A1 | |
| SCHEMBL1728042 | 0.80 | RXRA (0.46) | — | |
| SCHEMBL1727978 | 0.79 | KDM1A (0.43) | KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL1729688 | 0.79 | LMNA (0.59) | KDM4EMAPTDPP4DPP8DPP9 | |
| SCHEMBL1730249 | 0.79 | HTR3A (0.42) | LMNA | |
| SCHEMBL1729037 | 0.79 | HCAR2 (0.46) | MAPTDPP4DPP8DPP9DPP7 | |
| SCHEMBL1729289 | 0.78 | P4HTM (0.38) | KDM4EMAPTTP53ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |