SCHEMBL17280207

SCHEMBL17280207

CS(=O)(=O)c1cccc(-c2nc(-c3cccc(-c4c[nH]c(-c5cccc(S(C)(=O)=O)c5)n4)c3)c[nH]2)c1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GRK6 P43250 1/20 0.46
CTSS P25774 1/20 0.45
CTSK P43235 1/20 0.45
ATR Q13535 3/20 0.45
ALOX5 P09917 1/20 0.44
KCNH2 Q12809 2/20 0.44
TBK1 Q9UHD2 1/20 0.44
NPBWR1 P48145 1/20 0.43
CAMKK2 Q96RR4 2/20 0.42
SCD O00767 2/20 0.41
JAK2 O60674 1/20 0.40
PDPK1 O15530 1/20 0.40
GRM2 Q14416 1/20 0.40
PRKDC P78527 1/20 0.40
ATM Q13315 1/20 0.40
PLK4 O00444 1/20 0.40
LOXL2 Q9Y4K0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17280210 0.81 BRD4 (0.46) GRK6CTSSCTSK
SCHEMBL29662867 0.80 MAPK14 (0.56) NPBWR1SCD
SCHEMBL17280202 0.78 KMT2A (0.43) ATRALOX5NPBWR1GRM2
SCHEMBL17280220 0.77 ALDH1A1 (0.47) JAK2
SCHEMBL4657949 0.77 PSD (0.46) CTSSCTSKATRCAMKK2SCD
SCHEMBL4658974 0.77 NR1H2 (0.41) CTSSCTSKALOX5PLK4
SCHEMBL17279786 0.77 MEN1 (0.46) ATM
SCHEMBL4659178 0.76 NR1H2 (0.41) CTSSCTSKATRCAMKK2SCD
SCHEMBL4659067 0.75 SDHB (0.47)
SCHEMBL17280089 0.75 GRK6 (0.57) GRK6ALOX5TBK1PDPK1PLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020149206-A1 METHOD FOR PRODUCING ACRYLIC RESIN FILM コニカミノルタ株式会社 2020-07-23 WO disclosed
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 US disclosed
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE HRH3, HELZ, NBAS GRK6 3737/4885CTSS 1184/4885CTSK 1255/4885
US-10012777-B2 Resin composition NBAS, WDR5, HRH3 GRK6 4051/4885CTSS 1203/4885CTSK 2085/4885
US-20180203175-A1 TRIAZOLE COMPOUND H1-10, TTI2, H1-2 GRK6 2381/4885CTSS 3769/4885CTSK 1782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.