Sugi Predict

Sugi Predict / Compounds / SCHEMBL17280210

SCHEMBL17280210

SCHEMBL17280210

CCNS(=O)(=O)c1cccc(-c2c[nH]c(-c3cccc(-c4nc(-c5cccc(S(=O)(=O)NCC)c5)c[nH]4)c3)n2)c1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 4/20 0.46
▸ SYK P43405 2/20 0.45
▸ TDO2 P48775 1/20 0.42
▸ TNNI3K Q59H18 1/20 0.42
▸ GRK6 P43250 1/20 0.39
▸ CYP3A4 P08684 1/20 0.38
▸ ROCK1 Q13464 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ CTSS P25774 1/20 0.38
▸ CTSK P43235 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ LARS1 Q9P2J5 1/20 0.37
▸ GFER P55789 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17280207 0.81 GRK6 (0.46) GRK6CTSSCTSK
SCHEMBL17280099 0.79 GRK6 (0.48) BRD4SYKGRK6KMT2AALDH1A1
SCHEMBL17279971 0.77 BRD4 (0.46) BRD4SYKTNNI3KCYP3A4KMT2A
SCHEMBL17280220 0.71 ALDH1A1 (0.47) CYP3A4KMT2AALDH1A1
SCHEMBL17280174 0.71 METAP2 (0.41) KMT2ACTSSCTSKALDH1A1SMN1; SMN2
SCHEMBL17279786 0.70 MEN1 (0.46) KMT2AALDH1A1SMN1; SMN2
SCHEMBL13595012 0.70 GBA1 (0.56) BRD4KMT2AALDH1A1SMN1; SMN2
SCHEMBL17279780 0.69 MEN1 (0.43) KMT2AALDH1A1SMN1; SMN2
SCHEMBL350324 0.68 KMT2A (0.77) KMT2AALDH1A1
SCHEMBL31404044 0.68 KMT2A (0.77) KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020149206-A1 METHOD FOR PRODUCING ACRYLIC RESIN FILM コニカミノルタ株式会社 2020-07-23 — — WO disclosed
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 — — US disclosed
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 — — US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 — — US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 — — US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 — — US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE HRH3, HELZ, NBAS BRD4 691/4885SYK 3566/4885TDO2 791/4885
US-10012777-B2 Resin composition NBAS, WDR5, HRH3 BRD4 526/4885SYK 3757/4885TDO2 1362/4885
US-20180203175-A1 TRIAZOLE COMPOUND H1-10, TTI2, H1-2 BRD4 36/4885SYK 1324/4885TDO2 228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.