Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728819 | 0.90 | SLC6A7 (0.43) | DRD3HTR1ADRD4HTR2ASLC6A4 | |
| SCHEMBL1727895 | 0.89 | EGLN1 (0.43) | DRD3HTR1ADRD4HTR2ASLC6A4 | |
| SCHEMBL1728057 | 0.88 | MCHR1 (0.42) | DRD3HTR1ADRD4HTR2ASLC6A4 | |
| SCHEMBL1729147 | 0.85 | MGLL (0.43) | DRD3HTR1ADRD4HTR2ASLC6A4 | |
| SCHEMBL1728079 | 0.84 | DRD2 (0.42) | DRD3HTR1ADRD4HTR2AHRH2 | |
| SCHEMBL1729278 | 0.83 | HTR1A (0.41) | DRD3HTR1ADRD4HTR2ASLC6A4 | |
| SCHEMBL13136653 | 0.81 | SLC6A4 (0.46) | DRD3HTR1ADRD4HTR2ASLC6A4 | |
| SCHEMBL1730270 | 0.81 | EGLN1 (0.47) | DRD3HTR1ADRD4HTR2ASLC6A4 | |
| SCHEMBL1727526 | 0.80 | HRH2 (0.47) | DRD3HTR1ADRD4HTR2ASLC6A4 | |
| SCHEMBL1727880 | 0.80 | CNR2 (0.50) | DRD3HTR1ADRD4HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |