Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 3/20 | 0.32 |
| ▸ | GPR6 | P46095 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | CBLB | Q13191 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727576 | 0.87 | ABL1 (0.35) | ABL1AKT1CCR1CHRM4MAP3K5 | |
| SCHEMBL1729779 | 0.84 | SMO (0.34) | TRPV1DEGS1 | |
| SCHEMBL1730128 | 0.81 | HTR3A (0.43) | CHRM4TRPV1CNR1CNR2 | |
| SCHEMBL1729264 | 0.80 | HTR3A (0.41) | — | |
| SCHEMBL1730142 | 0.80 | ABL1 (0.37) | ABL1CHRM4 | |
| SCHEMBL1729370 | 0.78 | HRH3 (0.43) | — | |
| SCHEMBL1729453 | 0.77 | PDE10A (0.36) | — | |
| SCHEMBL1729308 | 0.77 | HRH3 (0.44) | — | |
| SCHEMBL1730195 | 0.76 | HCAR2 (0.46) | — | |
| SCHEMBL1727558 | 0.76 | KCNH2 (0.40) | DEGS1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |