Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729059 | 0.86 | DGAT1 (0.41) | KCNH2DGAT1KDM4EMAPTADORA2A | |
| SCHEMBL1729779 | 0.84 | SMO (0.34) | KCNH2DGAT1KDM4EMAPTADORA2A | |
| SCHEMBL1728999 | 0.84 | MGLL (0.41) | KCNH2DGAT1ADORA2AMGLLRAB9A | |
| SCHEMBL1727577 | 0.83 | PANK3 (0.38) | MAPTRAB9A | |
| SCHEMBL1729370 | 0.83 | HRH3 (0.43) | KCNH2DGAT1KDM4EADORA2A | |
| SCHEMBL1729308 | 0.81 | HRH3 (0.44) | KCNH2DGAT1MCHR1 | |
| SCHEMBL1727921 | 0.81 | KDM4E (0.43) | KDM4EMAPT | |
| SCHEMBL1729264 | 0.80 | HTR3A (0.41) | KCNH2DGAT1 | |
| SCHEMBL1727744 | 0.79 | RXRA (0.43) | — | |
| SCHEMBL1730195 | 0.79 | HCAR2 (0.46) | MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |