Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 5/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.44 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.44 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173049 | 0.85 | CFD (0.62) | CFDSMN1; SMN2TMEM97SIGMAR1F11 | |
| SCHEMBL19634734 | 0.80 | ALDH1A1 (0.58) | CFDSMN1; SMN2TMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL13875528 | 0.78 | SMN1; SMN2 (0.69) | SMN1; SMN2TMEM97SIGMAR1APPALDH1A1 | |
| SCHEMBL30086010 | 0.77 | MAPT (0.75) | — | |
| SCHEMBL24619547 | 0.77 | MAPT (0.75) | — | |
| SCHEMBL13060801 | 0.77 | FYN (0.55) | SMN1; SMN2TMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL1854346 | 0.76 | SMN1; SMN2 (0.66) | CFDSMN1; SMN2 | |
| SCHEMBL1638071 | 0.75 | DRD2 (0.68) | DRD2DRD4DRD3SMN1; SMN2TMEM97 | |
| Formic Acid SCHEMBL29924804 | 0.75 | MAPT (0.70) | — | |
| SCHEMBL11422348 | 0.74 | AOC3 (0.74) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768966-B1 | COUMPOUNDS AND METHODS FOR INHIBITING THE INTERACTION OF BCL PROTEINS WITH BINDING PARTNERS | INFINITY DISCOVERY INC (US) | 2012-03-07 | — | — | EP | disclosed |