Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 8/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.41 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | CYP46A1 | Q9Y6A2 | 4/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727929 | 0.82 | HRH4 (0.42) | PHGDHDPP4DPP7 | |
| SCHEMBL1730156 | 0.82 | DRD2 (0.41) | — | |
| SCHEMBL1729264 | 0.81 | HTR3A (0.41) | — | |
| SCHEMBL1730195 | 0.80 | HCAR2 (0.46) | DPP4DPP7HCRTR1HCRTR2 | |
| SCHEMBL1728165 | 0.80 | KDM4E (0.45) | — | |
| SCHEMBL1730128 | 0.79 | HTR3A (0.43) | — | |
| SCHEMBL1727921 | 0.78 | KDM4E (0.43) | — | |
| SCHEMBL1727724 | 0.78 | HSD11B1 (0.40) | — | |
| SCHEMBL1728682 | 0.77 | ACACB (0.40) | — | |
| SCHEMBL1727875 | 0.76 | ACACB (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |