Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17682027 | 0.86 | CA1 (0.43) | TSHRKDM4EALDH1A1TDP1CA1 | |
| SCHEMBL31364096 | 0.84 | CA1 (0.49) | TSHRMAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL235717 | 0.83 | LMNA (0.47) | TSHRMAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL29878896 | 0.82 | ALDH1A1 (0.44) | TSHRMAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL3099031 | 0.82 | ALDH1A1 (0.44) | TSHRMAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL32665524 | 0.77 | CA1 (0.47) | TSHRMAPK1ALDH1A1CA1CA2 | |
| SCHEMBL31204456 | 0.77 | CA1 (0.52) | TSHRMAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL15249772 | 0.75 | MEN1 (0.50) | TSHRMAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL11043528 | 0.75 | LMNA (0.54) | TSHRNPSR1KDM4EALDH1A1TDP1 | |
| SCHEMBL9463062 | 0.75 | LMNA (0.54) | TSHRNPSR1KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12390424-B2 | Sulfur (VI) fluoride compounds and methods for the preparation thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2025-08-19 | — | — | US | disclosed |
| EP-3715342-B1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | ZHONGHONGXIN INVEST HOLDINGS SHENZHEN CO LTD (CN) | 2024-08-07 | — | — | EP | disclosed |
| CN-111689929-B | Sulfur fluoride (VI) compound and preparation method thereof | 斯克里普斯研究所 | 2024-05-31 | — | — | CN | disclosed |
| EP-4295841-A2 | SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION | The Scripps Research Institute (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-3892610-B1 | SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION | SCRIPPS RESEARCH INST (US) | 2023-08-16 | — | — | EP | disclosed |
| US-20220313624-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-10-06 | — | — | US | disclosed |
| US-11230517-B2 | Method for aromatic fluorination | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2022-01-25 | — | — | US | disclosed |
| US-20220000799-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-01-06 | — | — | US | disclosed |
| EP-3892610-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE AS SCREENING AGENT | The Scripps Research Institute (US) | 2021-10-13 | — | — | EP | disclosed |
| US-11141385-B2 | Sulfur (VI) fluoride compounds and methods for the preparation thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-10-12 | — | — | US | disclosed |
| WO-2019101132-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海有机化学研究所 | 2019-05-31 | — | — | WO | disclosed |
| US-20190029972-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-01-31 | — | — | US | disclosed |
| US-10117840-B2 | Sulfur(VI) fluoride compounds and methods for the preparation thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-11-06 | — | — | US | disclosed |
| WO-2017192564-A1 | METHOD FOR AROMATIC FLUORINATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-11-09 | — | — | WO | disclosed |
| US-20170210695-A1 | METHOD FOR COUPLING A FIRST COMPOUND TO A SECOND COMPOUND | DOW AGROSCIENCES LLC | 2017-07-27 | — | — | US | disclosed |
| US-20170210695-A1 | METHOD FOR COUPLING A FIRST COMPOUND TO A SECOND COMPOUND | DOW AGROSCIENCES LLC | 2017-07-27 | — | — | US | disclosed |
| US-20170196985-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2017-07-13 | — | — | US | disclosed |
| EP-3151817-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | The Scripps Research Institute (US) | 2017-04-12 | — | — | EP | disclosed |
| WO-2016057770-A1 | METHOD FOR COUPLING A FLUOROSULFONATE COMPOUND WITH AN AMINE COMPOUND | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-04-14 | — | — | WO | disclosed |
| WO-2015188120-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170196985-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | CYP2F1, NAF1, CYP2S1 | TSHR 409/4885MAPK1 1862/4885NPSR1 341/4885 |
| US-12390424-B2 | Sulfur (VI) fluoride compounds and methods for the preparation thereof | GRB2, SCTR, OGFR | TSHR 7/4885MAPK1 3615/4885NPSR1 75/4885 |
| US-20220313624-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | QSOX1, YBX1, SFXN1 | TSHR 397/4885MAPK1 2006/4885NPSR1 1350/4885 |
| US-11230517-B2 | Method for aromatic fluorination | ARSA, AHR, AR | TSHR 530/4885MAPK1 3789/4885NPSR1 804/4885 |
| US-20220000799-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | PTMS, IGF2R, SCTR | TSHR 17/4885MAPK1 2801/4885NPSR1 195/4885 |
| US-20170210695-A1 | METHOD FOR COUPLING A FIRST COMPOUND TO A SECOND COMPOUND | PAICS, NUDT21, TIAL1 | TSHR 1912/4885MAPK1 1996/4885NPSR1 862/4885 |
| US-20190029972-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | HAX1, CYP2F1, CYP4X1 | TSHR 702/4885MAPK1 2512/4885NPSR1 583/4885 |
| US-11141385-B2 | Sulfur (VI) fluoride compounds and methods for the preparation thereof | CYP2F1, CYP2S1, NAF1 | TSHR 387/4885MAPK1 1554/4885NPSR1 431/4885 |
| US-10117840-B2 | Sulfur(VI) fluoride compounds and methods for the preparation thereof | CYP2F1, NAF1, CYP2S1 | TSHR 409/4885MAPK1 1862/4885NPSR1 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.